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NCLEX RN 2026 Comprehensive Clinical Practice Question Bank: Pharmacology, ABGs, Oxygen Therapy, Cardiac Care, Neurology, and Medical-Surgical Nursing with Detailed Rationales

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NCLEX RN Comprehensive Clinical Practice Question Bank: Pharmacology, ABGs, Oxygen Therapy, Cardiac Care, Neurology, and Medical-Surgical Nursing with Detailed Rationales

Institution
NCLEX RN
Course
NCLEX RN

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NCLEX RN Comprehensive Clinical Practice Question Bank 75
Q\A quiz
NCLEX RN Comprehensive Clinical Practice Question Bank: Pharmacology, ABGs, Oxygen
Therapy, Cardiac Care, Neurology, and Medical-Surgical Nursing with Detailed Rationales
Showing 75 questions (same pool and cap as a student attempt). Correct options are pre-
selected and highlighted as on the results page.
Bank category: NCLEX RN Comprehensive Clinical Practice Question Bank 75 Q\A

,1 Question 1



A client with an epidural suddenly develops severe headache and leakage of clear
fluid. What is the most likely complication?

☐ A. Pneumothorax


☑ B. Dural puncture


☐ C. Pulmonary embolism


☐ D. Myocardial infarction



RATIONALE
A severe headache with clear fluid leakage after epidural placement strongly suggests accidental
dural puncture, which can cause cerebrospinal fluid leakage and post-dural puncture headache.
KEY TERMS EXPLAINED
Epidural = Injection near the spinal cord for anesthesia
Dural puncture = Accidental puncture of the dura causing CSF leak
CSF = Cerebrospinal fluid surrounding brain and spinal cord

,2 Question 2



A nurse is teaching a client about allopurinol. Which instruction is
most appropriate?

☑ A. Continue taking it even when you are not having pain


☐ B. Stop it as soon as pain improves


☐ C. Use it only during sudden gout attacks


☐ D. Take double doses during flare-ups



RATIONALE
Allopurinol is used for long-term prevention of gout attacks by lowering uric acid levels. It should
be taken consistently, not only during attacks.
KEY TERMS EXPLAINED
Allopurinol = Medication used for long-term gout prevention
Gout flare = Sudden painful gout attack
Long-term therapy = Medication taken regularly to prevent recurrence

, 3 Question 3



A client asks why BNP is checked during heart failure treatment. What is the
best response?

☑ A. It helps show how much stress your heart is under


☐ B. It tells us if your blood sugar is normal


☐ C. It measures your kidney infection


☐ D. It checks your oxygen mask function



RATIONALE
BNP rises when the heart is stretched from pressure and fluid overload. It helps monitor the
severity of heart failure and treatment response.
KEY TERMS EXPLAINED
BNP = Hormone released with ventricular strain
Heart stress = Increased pressure and workload on the heart
Heart failure monitoring = Tracking severity and treatment response

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Institution
NCLEX RN
Course
NCLEX RN

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Uploaded on
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I provide nursing study resources, practice questions, rationales, summaries, NCLEX-style materials, HESI-style practice content, and revision guides designed to support exam preparation and topic understanding. All materials are prepared from study experience, topic review, and structured learning support. Feel free to message me if you have questions about a document before purchasing.

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