MEDICATIONS QUESTIONS WITH ANSWERS
LATEST UPDATE ALREADY GRADED A+
3 classes of classical/ FGA - correct answer- 1)
phenothiazines
2) thioxanthenes
3) butyrophenones
agent used to treat tardive dyskinesia - correct answer-
VMAT2 inhibitor (vesicular monoamine transporter 2)
1) deutetrabenazine
2) valbenazine
akathisia EPS with APs - correct answer- subjective
feeling of internal restlesness
objective signs of rocking, pacing, can't stay seated
AP known for causing akathisia - correct answer-
aripiprazole (ABILIFY)
, approach to prevent/ reduce harm with TD in SCZ patients -
correct answer- -use minimun effective dose of AP
-switch to agent with lower D2 blockade (clozapine, quetiapine)
-minimize anticholinergic agents
-baseline AIMS + biannually
APs with calorie requirements (2) - correct answer-
1) ziprasidone (500 cal)
2) lurasidone (350 cal)
at what receptors/ areas does aripiprazole act as an agonist? -
correct answer- -at presynaptic D2 receptors
-in regions where DA is low -- PFC in SCZ
at what receptors/ areas does aripiprazole act as an ANTagonist?
- correct answer- -at postsynaptic D2 receptors
-in regions where DA is high -- limbic regions in SCZ
black box warning for all antipsychotics - correct answer-
increased risk of death in elderly patients with dementia-related
psychosis