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NHISS GROUP C PATIENTS EXAM 2026 – 300+ PRACTICE QUESTIONS & ANSWERS (COMPREHENSIVE CLINICAL SCENARIOS)

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Pass your NHISS Group C certification exam on the first try with this comprehensive study guide. Over 300 real-style questions covering six complex patient scenarios: COPD exacerbation (BiPAP, ABG interpretation, pseudomonas, cor pulmonale), post-hemicolectomy (ileus, DVT/PE, anastomotic leak, evisceration, hemorrhage), acute pancreatitis (hypertriglyceridemia, necrosis, pseudocyst, ARDS, exocrine insufficiency), sickle cell crisis (acute chest syndrome, priapism, stroke, aplastic crisis, iron overload, hydroxyurea, gene therapy), end-stage liver disease (variceal bleed, ascites, SBP, hepatorenal syndrome, TIPS, encephalopathy, HCC), and septic shock (vasopressors, antibiotics, ARDS, CRRT, DIC, post-sepsis syndrome). Every question includes detailed rationales to help you understand the "why" behind the answer – not just memorize. Updated for 2026 NHISS standards. Perfect for nurses, paramedics, respiratory therapists, and critical care providers preparing for NHISS Group C certification. Download now and walk into your exam confident and ready!

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Page 1 of 127




NHISS GROUP C PATIENTS 1-6 PREP EXAM

2026 WITH COMPLETE SOLUTIONS (A NEW

UPDATED VERSION) |GUARANTEED PASS

A+ | PASS THE ACTUAL EXAM MUCH

EASIER




Q1. A nurse assesses Mr. Costa. Which finding is most

concerning?

A) Respiratory rate 24/min

B) SpO2 89% on 2L NC

C) Use of sternocleidomastoid muscles

D) Productive cough with green sputum

,Page 2 of 127


Answer: C – Accessory muscle use indicates respiratory

failure. SpO2 89% expected in COPD.

Q2. Provider orders BiPAP. Which initial settings are

appropriate?

A) IPAP 8 / EPAP 4

B) IPAP 20 / EPAP 18

C) IPAP 4 / EPAP 8

D) IPAP 15 / EPAP 5

Answer: A – Low IPAP/EPAP improve tolerance. High

pressures cause barotrauma.

Q3. Blood glucose 250 mg/dL. Lantus given. Correct action?

A) Hold all insulin

B) Give regular insulin per sliding scale

C) Give 50% dextrose IV

D) Recheck in 4 hours

Answer: B – Stress hyperglycemia requires correction. D50 for

hypoglycemia.

,Page 3 of 127


Q4. Spouse asks why O2 is only 2L. Best response:

A) “He needs higher O2 but doctor is conservative.”

B) “High oxygen can stop his drive to breathe.”

C) “We will increase it right away.”

D) “His lungs are damaged permanently.”

Answer: B – COPD patients may rely on hypoxic drive; high

FiO2 causes hypercapnia.

Q5. Which ABG finding supports BiPAP?

A) pH 7.38, PaCO2 48, PaO2 70

B) pH 7.31, PaCO2 62, PaO2 55

C) pH 7.45, PaCO2 38, PaO2 90

D) pH 7.35, PaCO2 45, PaO2 80

Answer: B – Acute respiratory acidosis (pH<7.35,

PaCO2>45) + hypoxemia.

Q6. Nebulized albuterol + ipratropium given. Finding

indicates effectiveness?

A) HR 88→110

, Page 4 of 127


B) SpO2 drops to 84%

C) Wheezing decreases, RR 32→18

D) Dry mouth

Answer: C – Decreased wheezing and RR indicates

bronchodilation.

Q7. New-onset confusion. Priority action?

A) Reorient

B) Check ABG, ask for BiPAP adjustment

C) Haloperidol

D) Increase O2 to 4L

Answer: B – Confusion suggests hypercapnia/hypoxemia.

ABG guides treatment.

Q8. BP 85/50. Which med should be held?

A) Albuterol neb

B) Lantus

C) Lisinopril

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