The phenomenon of disorganization of native protein
Structure is known as denaturation.Denaturation result
in the loss of secondary, tertiary and quaternary
structure of protein .This involves a change in Physical,
chemical and biological properties of protein
molecules.
, Denaturation occur due to physical
agent and chemical agent. Physical
agent like heat, violent shaking, x-
ray,uv radiation. Chemical agent like
acid ,alkali, organic solvent, salt of
heavy metal ,urea , detergent etc