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PHARMACY TECHNICIAN CERTIFICATION
EXAMINATION (NEW YORK) ACTUAL EXAM
2026/2027 COMPLETE ACCURATE EXAM
REAL QUESTIONS WITH WELL ELABORATED
ANSWERS. (100% CORRECT VERIFIED
SOLUTIONS)
1. A patient is prescribed lisinopril 10 mg daily. Which drug
class does this belong to?
A. Beta-blocker
B. ACE inhibitor
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C. ARB
D. Calcium channel blocker
Answer: B. ACE inhibitor
Rationale: Lisinopril ends in “-pril,” indicating an ACE inhibitor.
It lowers BP by blocking angiotensin-converting enzyme.
2. A prescription reads: “Metformin 500 mg BID.” What is the
daily dose?
A. 500 mg
B. 1000 mg
C. 1500 mg
D. 2000 mg
Answer: B. 1000 mg
Rationale: BID = two times per day → 500 mg × 2 = 1000
mg/day.
3. Scenario: A patient on warfarin starts taking St. John’s wort.
What effect?
A. Increased INR and bleeding risk
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B. Decreased INR, clot risk
C. No interaction
D. Increased warfarin absorption
Answer: B. Decreased INR, clot risk
Rationale: St. John’s wort induces CYP enzymes (2C9, 3A4),
reducing warfarin efficacy → lower INR, increased thrombosis
risk.
4. Which is a Schedule II controlled substance in NY?
A. Alprazolam
B. Codeine/acetaminophen 300/30 mg
C. Oxycodone
D. Gabapentin
Answer: C. Oxycodone
Rationale: Oxycodone is CII. Alprazolam = CIV. Codeine 30
mg combo = CIII. Gabapentin is not federally scheduled but
NY mandates reporting.
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5. A technician receives a prescription for “Nitroglycerin 0.4
mg sublingual tab PRN chest pain.” What counseling point?
A. Swallow whole with water
B. Place under tongue, may cause headache
C. Take with food
D. Refrigerate after opening
Answer: B. Place under tongue, may cause headache
Rationale: Sublingual absorption bypasses first-pass
metabolism. Headache is common due to vasodilation.
6. Which medication requires a MedGuide by federal law?
A. Metformin
B. Warfarin
C. Alendronate
D. Isotretinoin
Answer: D. Isotretinoin
Rationale: Isotretinoin (Accutane) has a REMS program
(iPLEDGE) requiring MedGuide dispensing.
PHARMACY TECHNICIAN CERTIFICATION
EXAMINATION (NEW YORK) ACTUAL EXAM
2026/2027 COMPLETE ACCURATE EXAM
REAL QUESTIONS WITH WELL ELABORATED
ANSWERS. (100% CORRECT VERIFIED
SOLUTIONS)
1. A patient is prescribed lisinopril 10 mg daily. Which drug
class does this belong to?
A. Beta-blocker
B. ACE inhibitor
,Page 2 of 94
C. ARB
D. Calcium channel blocker
Answer: B. ACE inhibitor
Rationale: Lisinopril ends in “-pril,” indicating an ACE inhibitor.
It lowers BP by blocking angiotensin-converting enzyme.
2. A prescription reads: “Metformin 500 mg BID.” What is the
daily dose?
A. 500 mg
B. 1000 mg
C. 1500 mg
D. 2000 mg
Answer: B. 1000 mg
Rationale: BID = two times per day → 500 mg × 2 = 1000
mg/day.
3. Scenario: A patient on warfarin starts taking St. John’s wort.
What effect?
A. Increased INR and bleeding risk
,Page 3 of 94
B. Decreased INR, clot risk
C. No interaction
D. Increased warfarin absorption
Answer: B. Decreased INR, clot risk
Rationale: St. John’s wort induces CYP enzymes (2C9, 3A4),
reducing warfarin efficacy → lower INR, increased thrombosis
risk.
4. Which is a Schedule II controlled substance in NY?
A. Alprazolam
B. Codeine/acetaminophen 300/30 mg
C. Oxycodone
D. Gabapentin
Answer: C. Oxycodone
Rationale: Oxycodone is CII. Alprazolam = CIV. Codeine 30
mg combo = CIII. Gabapentin is not federally scheduled but
NY mandates reporting.
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5. A technician receives a prescription for “Nitroglycerin 0.4
mg sublingual tab PRN chest pain.” What counseling point?
A. Swallow whole with water
B. Place under tongue, may cause headache
C. Take with food
D. Refrigerate after opening
Answer: B. Place under tongue, may cause headache
Rationale: Sublingual absorption bypasses first-pass
metabolism. Headache is common due to vasodilation.
6. Which medication requires a MedGuide by federal law?
A. Metformin
B. Warfarin
C. Alendronate
D. Isotretinoin
Answer: D. Isotretinoin
Rationale: Isotretinoin (Accutane) has a REMS program
(iPLEDGE) requiring MedGuide dispensing.
