NURS 5334 EXAM 3 (MODULE 8) QUESTIONS AND
ANSWERS
What type of bacteria is the primary cause for Peptic Ulcer Disease? - Answers - H.
pylori
What are the three ways Anti Ulcer Meds work? - Answers - 1. Antibiotics
2. Reduce Gastric Acidity
3. Enhance Mucosal defenses
What level does gastric pH need to be to decrease Pepsin Activity? - Answers - To
avoid activation of pepsin, raise gastric pH above 5
What are the three types of H. Pylori testing (Noninvasive)? - Answers - Breath Test
Serologic Test
Stool Test
What is an Invasive test for H. Pylori? - Answers - Gastric Mucosal Biopsies - performed
during EGD (biopsy urease test, histology, and much less commonly by bacteria
culture)
Endoscopic Specimens
How long should treatment be for Antibiotics therapy? - Answers - 10-14 days
According to the 2020 guidelines, what are the first line recommendations for the
treatment of Peptic Ulcer Disease? - Answers - 14 days of quadruple therapy with PPI,
Amoxicillin BID, Metronidazole BID, Clarithromycin BID
"MAC PP(i)s Twice a Day"
What is the alternative first-line Bismuth therapy for PUD? - Answers - PPI
Bismuth
Metronidazole
Tetracycline
What is the MOA of H2 receptor antagonists? - Answers - Block H2 receptor sites on
parietal cells reducing gastric acid secretion
What is the MOA of Proton pump inhibitors (PPI)? - Answers - Inhibits the enzyme that
generates gastric acid
Long term use it PPIs can cause deficiency in what mineral? - Answers - Magnesium
, Long term use of PPI can cause Hypomagnesemia
Proton Pump Inhibitors have what unique ending? - Answers - - prazole
Effects of PPI on calcium levels? - Answers - Lowers calcium levels
Risk of Fracture in older people
If on Proton Pump Inhibitors a patient need to report a fever and cough as soon as
possible, True or False? - Answers - True
What does Sucralfate do for duodenal and gastric ulcers? - Answers - Serves as a
protectant. When it comes in contact with gastric acid it created a paste and adheres to
the ulcerated area. This protects the ulcer from acid, pepsin and bile
What medication do you use to prevent gastric ulcers caused by the long term use of
NSAIDS? - Answers - Misoprostol
What are three uses for Misoprostol? - Answers - Medical abortion
Ripening of the Uterus
Prevention of Gastric Ulcers brought about by excess us of NSAIDS
Why should antacids be avoided in those with renal impairment? - Answers - Risk of
Magnesium Accumulation
What are the 4 Antacid Families? - Answers - Aluminum compounds
Magnesium compounds
Calcium compounds
Sodium compounds
MACS Antacids
Why should laxatives be taken with caution in pregnancy? - Answers - Laxatives should
be used with caution in pregnancy because the GI stimulation can induce labor.
Laxatives should be used with caution when breastfeeding because the laxative can be
excreted in the breast milk
What type of Laxative is Methylcellulose and Psyllium? - Answers - Bulk forming
laxative
How do bulk forming laxatives work? - Answers - Produce large soft stool which
stimulates peristalsis
How long does it take for Bulk forming Laxatives to work? - Answers - 1-3 days
Name a surfactant laxative - Answers - docusate sodium
ANSWERS
What type of bacteria is the primary cause for Peptic Ulcer Disease? - Answers - H.
pylori
What are the three ways Anti Ulcer Meds work? - Answers - 1. Antibiotics
2. Reduce Gastric Acidity
3. Enhance Mucosal defenses
What level does gastric pH need to be to decrease Pepsin Activity? - Answers - To
avoid activation of pepsin, raise gastric pH above 5
What are the three types of H. Pylori testing (Noninvasive)? - Answers - Breath Test
Serologic Test
Stool Test
What is an Invasive test for H. Pylori? - Answers - Gastric Mucosal Biopsies - performed
during EGD (biopsy urease test, histology, and much less commonly by bacteria
culture)
Endoscopic Specimens
How long should treatment be for Antibiotics therapy? - Answers - 10-14 days
According to the 2020 guidelines, what are the first line recommendations for the
treatment of Peptic Ulcer Disease? - Answers - 14 days of quadruple therapy with PPI,
Amoxicillin BID, Metronidazole BID, Clarithromycin BID
"MAC PP(i)s Twice a Day"
What is the alternative first-line Bismuth therapy for PUD? - Answers - PPI
Bismuth
Metronidazole
Tetracycline
What is the MOA of H2 receptor antagonists? - Answers - Block H2 receptor sites on
parietal cells reducing gastric acid secretion
What is the MOA of Proton pump inhibitors (PPI)? - Answers - Inhibits the enzyme that
generates gastric acid
Long term use it PPIs can cause deficiency in what mineral? - Answers - Magnesium
, Long term use of PPI can cause Hypomagnesemia
Proton Pump Inhibitors have what unique ending? - Answers - - prazole
Effects of PPI on calcium levels? - Answers - Lowers calcium levels
Risk of Fracture in older people
If on Proton Pump Inhibitors a patient need to report a fever and cough as soon as
possible, True or False? - Answers - True
What does Sucralfate do for duodenal and gastric ulcers? - Answers - Serves as a
protectant. When it comes in contact with gastric acid it created a paste and adheres to
the ulcerated area. This protects the ulcer from acid, pepsin and bile
What medication do you use to prevent gastric ulcers caused by the long term use of
NSAIDS? - Answers - Misoprostol
What are three uses for Misoprostol? - Answers - Medical abortion
Ripening of the Uterus
Prevention of Gastric Ulcers brought about by excess us of NSAIDS
Why should antacids be avoided in those with renal impairment? - Answers - Risk of
Magnesium Accumulation
What are the 4 Antacid Families? - Answers - Aluminum compounds
Magnesium compounds
Calcium compounds
Sodium compounds
MACS Antacids
Why should laxatives be taken with caution in pregnancy? - Answers - Laxatives should
be used with caution in pregnancy because the GI stimulation can induce labor.
Laxatives should be used with caution when breastfeeding because the laxative can be
excreted in the breast milk
What type of Laxative is Methylcellulose and Psyllium? - Answers - Bulk forming
laxative
How do bulk forming laxatives work? - Answers - Produce large soft stool which
stimulates peristalsis
How long does it take for Bulk forming Laxatives to work? - Answers - 1-3 days
Name a surfactant laxative - Answers - docusate sodium
