Guide DRAFT Questions With Complete Solutions
-Acetaminophen --> either by itself or in combo with other
drugs (ie. APAP/Norco, Percocet) ***
-Amiodarone
-Bromfenac (a kind of eye drops)
- Cyclosporine (immunosuppressant for cancer)
-Methotrexate (anti-inflammatory for osteoarthritis)
-Niacin (vitamin B3 often used for energy)
-Oral contraceptives Correct Answers What are common drugs
that cause drug-induced liver injury (DILI)?
-AST = 9-40
-ALT = 7-60
-Bilirubin = <1
-Albumin = 3.4-5.4
-PT = 11-13 sec.
-INR = 1 Correct Answers What are the normal ranges for liver
function tests?
-Bililight (changes the shape and structure of bilirubin to create
a form that is able to be more easily excreted in pee and poop)
-Blood transfusions
-Antibody injection (IV immunoglobulins) to prevent/decrease
baby RBCs being destroyed Correct Answers How is HDN
treated?
-Cerebral edema
-Increased ICP Correct Answers What are s/s of hypotonic IVF
overload?
,-Chills
-Fever
-Chest pain
-Lower back pain
-Trali (acute lung injury) --> difficulty breathing with a fever
-Taco (circulatory overload) --> no fever, but s/s of a circulatory
overload such as JVD Correct Answers What are s/s of a
transfusion reaction?
-Dry mouth and increased thirst (RAAS holds onto more fluid
due to decreased BP)
-Abdominal pain and swelling
-Jaundice
-Weight loss Correct Answers What are s/s of alcoholic
hepatitis?
-Early stage --> Non-Alcoholic Fatty Liver Disease (NAFLD);
buildup of fat in liver that is REVERSIBLE
-Later stage --> Non-Alcoholic Steatohepatitis (NASH); more
severe form of fatty liver
-Toxic stage --> built up fat becomes toxic, killing off liver cells
and leading to an inflamed and fibrotic liver, which can become
cirrhosis (IRREVERSIBLE) Correct Answers What are the
stages of steatosis/fatty liver disease?
-EPO (hormone that stimulates RBC production when there's
low blood O2 levels)
-Albumin (plasma protein important for maintaining oncotic
pressure)
-Bile (helps with fat digestion)
, -Bilirubin (yellow pigment produced from old RBCs)
-Globulins (gamma/immunoglobulins for immunity)
-Lipoproteins (help with fat soluble vitamins
-Prothrombin (helps with blood clotting)
-Vitamin K (helps with blood clotting) Correct Answers What
does the liver produce?
-Fat-soluble vitamins (Vitamins A, D, E, and K) --> deficiencies
are common due to malabsorption, decreased intake, and
decreased production of carrier proteins
-Water soluble vitamins (thiamine/B1, pyridoxine/B6, folate/B9,
cobalamin/B12, zinc, and magnesium) --> deficiencies common
due to decreased hepatic storage, malabsorption, and decreased
intake Correct Answers What multivitamin supplements may
be given for cirrhosis?
-Fever
-Fatigue
-N/V
-Anorexia (loss of appetite)
-Change in taste
-Hyperbilirubinemia (due to bilirubin being blocked from
entering stool) --> dark urine, pale stools, and diarrhea
-Jaundice
-Stomach pain
-Weight loss
-Pruritus
-Bleeding and bruising easily
-Abnormal liver function tests