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What is the primary function of the immune system? - Answer- To defend the body from
agents and disease.
What is the lymphatic system? - Answer- A network of organs and vein-like vessels that
recover fluid, inspect for disease agents, activate immune responses, and return fluid to
the bloodstream.
Name the eleven lymph trunks. - Answer- Jugular, Subclavian, Bronchomediastinal,
Intercostal, Intestinal, Lumbar.
What are neutrophils? - Answer- Antibacterial cells that are part of the immune
response.
What are natural killer (NK) cells? - Answer- Large lymphocytes that attack and destroy
bacteria, transplanted tissue, and host cells infected with viruses or that have turned
cancerous.
Where do T lymphocytes (T cells) mature? - Answer- In the thymus.
What do B lymphocytes (B cells) differentiate into upon activation? - Answer- Plasma
cells that produce antibodies.
What are macrophages? - Answer- Large, phagocytic cells that process foreign matter
and display antigenic fragments to T cells.
What are dendritic cells? - Answer- Mobile antigen presenting cells found in the
epidermis, mucous membranes, and lymphatic organs.
What are reticular cells? - Answer- Stationary cells that contribute to the stroma of a
lymphatic organ.
What are the primary lymphatic organs? - Answer- Red bone marrow and thymus.
What are secondary lymphatic organs? - Answer- Lymph nodes, tonsils, and spleen.
What is lymphadenitis? - Answer- Swollen painful lymph nodes responding to foreign
antigens.
What is lymphadenopathy? - Answer- A collective term for all lymph node diseases.
, What is metastasis? - Answer- The process by which cancerous cells break free from
the original tumor and establish new tumors in other sites.
What is the function of tonsils? - Answer- To guard against ingested or inhaled
pathogens.
What are the three main sets of tonsils? - Answer- Palatine tonsils, Lingual tonsils,
Pharyngeal tonsil (adenoids).
What is the spleen's role in the body? - Answer- It monitors blood for foreign antigens
and stabilizes blood volume through plasma transfers to the lymphatic system.
What are the three lines of defense against pathogens? - Answer- First line: Skin and
mucous membranes; Second line: Innate defense mechanisms; Third line: Adaptive
immunity.
What is innate immunity? - Answer- The body's immediate defense against a broad
range of pathogens without memory.
What are the protective proteins in innate immunity? - Answer- Dermicidin, defensins,
and cathelicidins.
What is adaptive immunity? - Answer- The body's ability to develop specific immunity to
each pathogen and retain memory of it.
What are phagocytes? - Answer- Cells that engulf foreign matter.
What are the five types of leukocytes? - Answer- Neutrophils, Eosinophils, Basophils,
Monocytes, Lymphocytes.
What do basophils secrete? - Answer- Chemicals that aid the mobility and action of
other leukocytes, including histamine and heparin.
What is the macrophage system? - Answer- All the body's avidly phagocytic cells,
except leukocytes.
What are the two families of antimicrobial proteins? - Answer- Interferons and other
proteins that inhibit microbial reproduction.
What is the role of the complement system in immunity? - Answer- It contributes to both
innate and adaptive immunity through pathogen destruction.
Name the four methods of pathogen destruction via activated complement. - Answer-
Inflammation, immune clearance, phagocytosis, and cytolysis.