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Which type of hypersensitivity response is mediated by T cells?
A. Hypersensitivity type I
B. Hypersensitivity type II
C. Hypersensitivity type III
D. Hypersensitivity type IV
A. Hypersensitivity type IV
- Type IV hypersensitivity is mediated by T cells. Hypersensitivity types I, II,
and III are mediated by antibodies produced by B lymphocytes.
A severe life-threatening type I hypersensitivity reaction is
A. Angioedema
B. Urticaria
C. Anaphylaxis
D. Hives
C. Anaphylaxis
,What is the pathophysiologic abnormality underlying systemic lupus
erythematosus (SLE)?
A. Type II hypersensitivity
B. Immunosuppression
C. Immune deficiency
D. Autoimmunity
D. Autoimmunity
- SLE is a type III hypersensitivity reaction caused by autoantibody
production and occurs when the immune system recognizes a person's
own cells ("self") as foreign and mounts an immune response that injures
self tissues.
Bronchiectasis is associated with
cystic fibrosis
Bronchiectasis is
both an obstructive and suppurative (pus-forming) disorder
S/s of bronchiectasis include
chronic productive cough, coughing up sputum and blood, fever, crackles
Cystic fibrosis as an
Autosomal recessive disorder of exocrine glands
,The pathogensis of cystic fibrosis involves
the dysfunction of CFTR gene
The hypersecretion of abnormal, thick mucus that obstructs exocrine
glands and ducts occurs in
Cystic fibrosis
α1 Antitrypsin deficiency is a genetic risk factor for
Emphysema (Type A COPD)
S/s for emphysema include
digital clubbing, dyspnea, and barrel chest
Damage to the alveolar-capillary membrane is a hallmark for
Acute (Adult) Respiratory Distress Syndrome (ARDS)
The collection of fluid or pus in pleural cavity as result of another disease
process
Pleural effusion
Renal artery stenosis reduces ______, which _ blood volume and BP
glomerular filtratoin rate, increases
, Hyperaldosteronism is the most common cause of adult
secondary hypertension
Renal artery stenosis, pheochromocytoma, pregnancy, obesity/obstructive
sleep apnea and hyperaldosteronism are common causes of
adult secondary hypertension
sudden increase in either or both systolic or diastolic blood pressure with
evidence of end-organ damage defines
hypertensive emergency
sudden blood pressure elevation without evidence of end-organ damage
defines
hypertensive urgency
Increased LDL levels contributes to
coronary artery disease
Chest pain associated with intermittent myocardial ischemia during
moderate physical activity is called
Stable angina