PATH 3610 Final Exam Review
Questions and Answers
Death of cells in a living organism is termed:
1) Gangrene
2) Necrosis
3) Ischemia - ANSWERS-Necrosis
Apoptosis refers to:
1) The internalization of material by a cell
2) Disintegration of tissues which occurs after death
3) Programmed cell death - ANSWERS-Programmed cell death
A myocardial infarct is seen as a dry, well demarcated area of pale tissue. This would be
described as:
1) Coagulation necrosis
2) Caseation necrosis
3) An abscess - ANSWERS-Coagulation necrosis
Free radicals can impair cell membrane function by causing:
1) Lesions in DNA
,2) Lipid peroxidation
3) Protein cross-linking - ANSWERS-Lipid peroxidation
Starvation can lead to the development of fatty liver.
True or false? - ANSWERS-True
Regional tissue necrosis due to ischemia, followed by secondary bacterial infection defines:
1) Autolysis
2) Putrefaction
3) Gangrene - ANSWERS-Gangrene
Hypoxia, leading to impaired energy production by the cell, may be caused by:
1) Anemia
2) Low blood glucose levels
3) Inhibition of respiratory enzymes - ANSWERS-Anemia
The primary change in hemolytic jaundice is:
1) Inadequate bilirubin excretion
2) Increased production of bilirubin
3) Serum accumulation of conjugated bilirubin - ANSWERS-Increased production of bilirubin
Bilirubin is:
,1) Lipid soluble when conjugated
2) Water soluble when conjugated
3) Conjugated in the kidney for excretion in the urine - ANSWERS-Water soluble when
conjugated
Cellular injury can result when bilirubin accumulates in:
1) Parenchymal cells (such as the liver or brain)
2) Connective tissue
3) Skin - ANSWERS-Parenchymal cells (such as the liver or brain)
Anemia will lead to impaired energy production by the cell because there is:
1) Insufficient oxygen
2) Low glucose levels
3) Enzyme inhibition - ANSWERS-Insufficient oxygen
Ischemia refers to:
1) A reduction of failure of blood supply to tissues
2) The death of tissues due to inadequate blood supply
3) Insufficient oxygenation of tissues due to poor blood supply - ANSWERS-A reduction of failure
of blood supply to tissues
With vascular injury, platelets are exposed to the extracellular matrix, which induces platelet
adhesion via interaction with:
, 1) von Willebrand factor
2) Thromboxane
3) ADP - ANSWERS-von Willebrand factor
The "economy class syndrome" occurs with prolonged air travel in cramped seating. The
described thrombosis occurs because there is:
1) Increased viscosity of blood due to poor oxygenation
2) Increased turbulence of blood flow
3) Stasis of blood flow in veins of the legs - ANSWERS-Stasis of blood flow in veins of the legs
Transient arteriolar vasoconstriction in early hemostasis is primarily due to:
1) Local secretion of vasoconstrictors
2) Reflex neurogenic mechanisms
3) Platelet-derived factors - ANSWERS-Reflux neurogenic mechanisms
Which of the following statements regarding thrombosis is false?
1) Thrombus formation is favoured by both dehydration and inactivity
2) Pre-existing vascular disease would predispose to the development of thrombosis
3) Taking aspirin increases the risk of thrombus formation - ANSWERS-Taking aspirin increases
the risk of thrombus formation
Edema may be the result of:
Questions and Answers
Death of cells in a living organism is termed:
1) Gangrene
2) Necrosis
3) Ischemia - ANSWERS-Necrosis
Apoptosis refers to:
1) The internalization of material by a cell
2) Disintegration of tissues which occurs after death
3) Programmed cell death - ANSWERS-Programmed cell death
A myocardial infarct is seen as a dry, well demarcated area of pale tissue. This would be
described as:
1) Coagulation necrosis
2) Caseation necrosis
3) An abscess - ANSWERS-Coagulation necrosis
Free radicals can impair cell membrane function by causing:
1) Lesions in DNA
,2) Lipid peroxidation
3) Protein cross-linking - ANSWERS-Lipid peroxidation
Starvation can lead to the development of fatty liver.
True or false? - ANSWERS-True
Regional tissue necrosis due to ischemia, followed by secondary bacterial infection defines:
1) Autolysis
2) Putrefaction
3) Gangrene - ANSWERS-Gangrene
Hypoxia, leading to impaired energy production by the cell, may be caused by:
1) Anemia
2) Low blood glucose levels
3) Inhibition of respiratory enzymes - ANSWERS-Anemia
The primary change in hemolytic jaundice is:
1) Inadequate bilirubin excretion
2) Increased production of bilirubin
3) Serum accumulation of conjugated bilirubin - ANSWERS-Increased production of bilirubin
Bilirubin is:
,1) Lipid soluble when conjugated
2) Water soluble when conjugated
3) Conjugated in the kidney for excretion in the urine - ANSWERS-Water soluble when
conjugated
Cellular injury can result when bilirubin accumulates in:
1) Parenchymal cells (such as the liver or brain)
2) Connective tissue
3) Skin - ANSWERS-Parenchymal cells (such as the liver or brain)
Anemia will lead to impaired energy production by the cell because there is:
1) Insufficient oxygen
2) Low glucose levels
3) Enzyme inhibition - ANSWERS-Insufficient oxygen
Ischemia refers to:
1) A reduction of failure of blood supply to tissues
2) The death of tissues due to inadequate blood supply
3) Insufficient oxygenation of tissues due to poor blood supply - ANSWERS-A reduction of failure
of blood supply to tissues
With vascular injury, platelets are exposed to the extracellular matrix, which induces platelet
adhesion via interaction with:
, 1) von Willebrand factor
2) Thromboxane
3) ADP - ANSWERS-von Willebrand factor
The "economy class syndrome" occurs with prolonged air travel in cramped seating. The
described thrombosis occurs because there is:
1) Increased viscosity of blood due to poor oxygenation
2) Increased turbulence of blood flow
3) Stasis of blood flow in veins of the legs - ANSWERS-Stasis of blood flow in veins of the legs
Transient arteriolar vasoconstriction in early hemostasis is primarily due to:
1) Local secretion of vasoconstrictors
2) Reflex neurogenic mechanisms
3) Platelet-derived factors - ANSWERS-Reflux neurogenic mechanisms
Which of the following statements regarding thrombosis is false?
1) Thrombus formation is favoured by both dehydration and inactivity
2) Pre-existing vascular disease would predispose to the development of thrombosis
3) Taking aspirin increases the risk of thrombus formation - ANSWERS-Taking aspirin increases
the risk of thrombus formation
Edema may be the result of:
