VERSIONS 2025-2026 (VERSION A& B)
/ NR 507 WEEK 4 MIDTERM
ADVANCED PATHOPHYSIOLOGY
MIDTERM EXAM WITH CORRECT
VERIFIED AND WELL ANALYZED
ANSWERS GRADED A+
Examples of hypersensitivity type 1
allergic rhinitis, anaphylactic reaction
Type 1 hypersensitivity reactions are mediated by what
IgE
What cells are involved in hypersensitivity type 1
Mast cells
symptoms of hypersensitivity type 1
local: itching, immediate rash
systemic: wheezing
main treatment for anaphylaxis
epinephrine
Type 2 hypersensitivity is also known as what kind of reaction?
cytotoxic reaction, tissue specific
, what cells are involved in type 2 hypersensitivity reaction?
Macrophages
what does type 2 hypersensitivity do to tissues?
can cause damage or alter function of specific tissues
Examples of hypersensitivity type 2
graves’ disease/ hyperthyroidism, blood incompatibility
what is the difference between type 2 and 3 hypersensitivity?
type 2 is organ specific; antibody binds to the antigen on the surface
of the cell
type 3 is NOT organ specific; binds outside of the cell surface and is
released into blood/ body fluids and then deposited into tissues
examples of type 3 hypersensitivity
rheumatoid arthritis and lupus
autoimmune diseases can be...
genetic/familial
What is all immunity?
Immune reaction to tissues of another individual
Examples of all immunity
transplant rejection, transfusion reactions, Rh incompatibility
what is hypersensitivity type 4
Delayed response, occurs 24-72 hrs. after exposure
does not involve antigen/antibody complexes
Hypersensitivity type 4 is mediated by what?
T cells!!!
example of hypersensitivity type 4
contact dermatitis
poison ivy
delayed response occurs in area of contact