And Answers Verified 100% Correct
Vicodin has been changed from a Schedule _____ to a Schedule____drug due to
its increased risk of abuse and addiction. - ANSWER -III to II
1. List two (2) different Schedule I substances (of which NPs are not permitted to
prescribe). - ANSWER -Marijuana, Heroin, Peyote, LSD, Ecstasy.
What class of pain medications typically should not be ordered for a renal-
impaired patient (GFR < 50 ml/min)? - ANSWER -NSAIDS. NSAIDs and higher
doses of Aspirin are not recommended for those with kidney impairment.
In general, lowest effective dose should be prescribed.
What class of pain medications typically should not be ordered for a moderately
hepatic-impaired patient, or must be hepatic dosed adjusted? - ANSWER -
Acetaminophen. Drugs with Acetaminophen combination (Hydrocodone,
oxycodone combos)
According to the Pharmacotherapeutics for Advanced Practice Providers textbook,
pure opioid agonists such as Morphine have the effects such as respiratory
depression. From your textbook, list 5 more possible effects of pure opioid
agonists. - ANSWER -Hypotension Confusion
SedationNauseaVomitingHallucinations
EuphoriaDepression of cough reflexes
ParesthesiaMiosisConstipationNeurotoxicity
Cough medications with codeine or antidiarrheal are what type of Scheduled
medication? - ANSWER -Schedule V.
Cough medicines containing no more than 200 milligrams of codeine per 100
milliliters or per 100 grams
Benzodiazepines must be (fill in the blank) when you plan to discontinue them?
Here's your choices- Abruptly stopped, tapered, dosed around the clock to be
, effective, or have thorough renal and hepatic labs before prescribing. - ANSWER -
Tapered. Per UpToDate (2021), reduce the dose by 50 percent every two to four
weeks, with monitoring at each dose reduction and at two to four weeks after
cessation. In addition, stop one drug at a time.
How many refills can a patient have for Methylphenidate (Ritalin)? - ANSWER -
No refills. They must be ordered every time with a new prescription. It is a
schedule II stimulant.
What are the unique characteristics of Oxycodone (Oxycontin), aside from its
potency? What Controlled Drug Schedule is it? - ANSWER -Schedule II. No
refills must be electronically prescribed, in many areas.
OxyContin is time released.
Oxycodone products can be administered IM, IV, SQ, PO, PR.
OxyContin PO can remain effective for up to 12 hours, making it the longest acting
oxycodone product available.
In 2010, it was reformulated to include hard coating on the outside that makes
tablets difficult to crush, dissolve or break. It also forms a gel when combined with
water, aimed at preventing abuse by snorting or injection.
While legal doses vary by patient, a typical dose prescribed by a clinician ranges
from two to four tablets daily. Four dosages available:10, 20, 40, and 80 mg
The chemical structure of oxycodone is very similar to codeine.
Oxycodone works on the CNS, altering the sense of pain and emotional response
to pain.
Side effects include: anxiolysis, euphoria, feelings of relaxation, respiratory
depression, constipation, miosis, and cough suppression, as well as analgesia.
Crushing could cause fatally high doses.
Very high rate of conversion to heroin.
Abusers of OxyContin prior to reformulation did not cease drug abuse because of
the abuse deterrent formulation.
It was originally marketed in the late nineties as "not addicting" and many clinics
were opened just to write OxyCODONE prescriptions.
What are the signs and symptoms of opiate withdrawal? - ANSWER -Abdominal
cramps, diarrhea, nausea, and/or vomiting.