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Summary Pharm Exam 1 Review Lecture Notes 1‑2 – Study Guide

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This study guide provides a thorough review of Pharm Exam 1, summarizing lecture notes from units 1 and 2. It covers essential pharmacological concepts including drug classes, mechanisms of action, indications, contraindications, side effects, and nursing considerations. Use these concise notes to reinforce your understanding and prepare effectively for your exam.

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lOMoARcPSD|11700591




 The Nursing Process
o An organizational framework for the practice of nursing.
 Steps:
 Assessment
 Data collection, review & analysis
 Medication profile
 Diagnosis
 Used to communicate and share info about the patient and the
patient experience
 Common diagnoses:
 Deficient knowledge
 Risk for injury
 noncompliance
 Planning
 Goals - objective, measurable, and realistic with an established
time period for achievement of the outcomes that are specifically stated in
the outcome criteria
 Outcome Criteria - concrete description of patient goals
 Implementation
 Initiation and completion of specific nursing actions as defined
by the nursing diagnoses, goals and outcome criteria
 Follow the 6 rights of med administration
 Right drug, dose, time, route, patient & documentation
 Evaluation
 Ongoing part of the nursing process
 Determining the status of the goals and outcomes of care
 Monitor the patients response to drug therapy

 Subjective Data
o Includes all spoken information shared by the patient
o Such as:
 Complaints
 Problems
 Or stated needs

 Objective Data
o Includes information available through senses, such as what is seen, felt, heard, and
smelled.
o Among the sources of data are:
 The chart
 Lab results
 Report of diagnostic procedures
 Physical assessment
 Examination findings
o Examples:
 Age
 Height

, lOMoARcPSD|11700591




 Weight
 Allergies
 Med profile
 Health history

 Pharmacokinetics - the study of what the body does to the drug (think MOVEMENT)
o Four major pharmacokinetic processes
 Absorption
 Bioavailability
 First pass effect - the initial metabolism in the liver of a drug absorbed
from the gastrointestinal tract before the drug reaches systemic circulation
through the bloodstream
 Different routes
 Distribution
 Transport of a drug by the bloodstream to its site of action
 Albumin is the most common blood protein & carries the majority of
protein-bound drug molecules
 Metabolism (Biotransformation)
 Biochemical alteration of a drug into an inactive metabolite, more
soluble compound, more potent active metabolite, or a less active metabolite.
 Excretion
 Elimination of drugs from body
 Renal Excretion - Kidneys are a primary source of excretion
o Half-life - time required for 50% of a given drug to be removed from body

 Pharmacodynamics - the study of what the drug does to the body
o Mechanism of drug actions in living tissues
o Therapeutic effect
o Mechanism of action (MOA)

 Lifespan Considerations
o Fetus
 Drugs cross the placenta by diffusion
 FDA has implemented pregnancy safety categories
o Infants (Neonatal & Pediatric)
 Breastfed infants are at risk for exposure to drugs consumed by the mother
 Consider risk-benefit ratio
 Pharmacokinetics
 Absorption
 Gastric pH less acidic until 1-2 yr old
 Gastric emptying slowed
 IM absorption faster & irregular
 Distribution
 Greater total body water = lower fat content
 Decreased level of protein binding
 Immature BBB - more drugs enter brain
 Metabolism

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