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,natural immunity (innate or native) - Answer: type of immunity
that includes physical barriers (e.g., skin), phagocytic cells, and
natural killer cells. All of these factors are present before
exposure to a particular infectious agent, and all respond
nonspecifically.
specific acquired immunity - Answer: Immunity in which
responses occur only after exposure to a foreign substance.
Objective is to destroy antigens
Antigens - Answer: The foreign substances that induce specific
responses in specific acquired immunity
Cell-mediated, Humoral (antibody-mediated) - Answer: the two
classes of specific acquired immunity
Cell-mediated immunity - Answer: refers to immune responses
in which targets are attacked directly by immune system cells—
specifically, cytolytic T cells and macrophages
Humoral immunity - Answer: refers to immune responses that
are mediated by antibodies.
,B lymphocytes - Answer: have the job of making antibodies.
Hence mediates humoral immunity. produced in the bone
marrow.
Cytolytic T Cells - Answer: attack and kill target cells directly,
mature in the thymus
Helper T cells - Answer: contribute to the immune response in
three ways: (1) they have an essential role in antibody
production by B cells; (2) they release factors that promote
type IV sensitivity reactions, also known as delayed-type
hypersensitivity (DTH); and (3) they participate in the activation
of cytolytic T cells.
Are the immune cell that HIV attacks
Mature in the thymus
Macrophages - Answer: Present in all organs and tissues,
primary role is phagocytosis, (1) they are required for activation
of T cells (both helper T cells and cytolytic T cells), (2) they are
the final mediators of DTH, and (3) they phagocytize cells that
have been tagged with antibodies
, Dendritic Cells - Answer: perform the same antigen-presenting
task as do macrophages, but do not act as scavengers
Mast cells - Answer: These cells mediate immediate
hypersensitivity reactions, derived from basophils,
concentrated in the skin and other soft tissues, release
histamine, heparin, and other compounds that cause the
symptoms of immediate hypersensitivity
Basophils - Answer: These cells mediate immediate
hypersensitivity reactions, circulate in the blood, release
histamine, heparin, and other compounds that cause the
symptoms of immediate hypersensitivity
Neutrophils - Answer: phagocytize bacteria and other foreign
particles, avidly devour cells that have been tagged with
antibodies of the immunoglobulin G (IgG) class, major
contributors to inflammation
Eosinophils - Answer: attack and destroy foreign particles that
have been coated with antibodies of the IgE class. Their usual
target is helminths (parasitic worms). also contribute to tissue
injury and inflammation associated with immediate
hypersensitivity reactions.