Illinois Pharmacy Law Examination (MPJE)
Practice Questions And Correct Answers
(Verified Answers) Plus Rationales 2026 Q&A
| Instant Download |Verified Answers*
Illinois Pharmacy Law Examination (MPJE) Practice Exam
Domain 1: Licensure & Regulatory Authority
1. Which agency is primarily responsible for licensing pharmacists and enforcing the
Illinois Pharmacy Practice Act?
A. Illinois Department of Public Health (IDPH)
B. Drug Enforcement Administration (DEA)
C. Illinois Department of Financial and Professional Regulation (IDFPR)
D. Board of Pharmacy Specialties
<details> <summary>Answer & Rationale</summary> **Answer: C** *Rationale:* The
IDFPR, through the Division of Professional Regulation, oversees the licensure, registration,
and discipline of pharmacists and pharmacies in Illinois[citation:3]. </details>
2. According to a 2024 rule amendment effective January 1, 2026, what is required of a
Pharmacist-in-Charge (PIC) for an out-of-state (non-resident) pharmacy shipping into
Illinois?
A. Must visit the Illinois facility once per year
B. Must be licensed as a pharmacist in Illinois
C. Must hold a Doctor of Pharmacy degree
D. Must designate a local agent in Chicago
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:*
Specifically for 2026, the Illinois regulations (Ill. Admin. Code tit. 68, § 1330.550) mandate
that PICs of non-resident pharmacies must be licensed in Illinois, effective Jan 1, 2026.
</details>
,Domain 2: The Illinois Pharmacy Practice Act (PPA)
3. Under the Illinois Pharmacy Practice Act, what is required for a pharmacy technician to
practice in the state?
A. Certification by the PTCB only
B. Registration with the IDFPR
C. Completion of a 4-year degree
D. Direct employment by a hospital
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Illinois
law requires pharmacy technicians to be registered with the IDFPR. Certification (CPhT) is
required within two years of registration, but registration is the primary legal requirement.
</details>
4. A pharmacy intern in Illinois must practice under the direct supervision of:
A. A registered nurse
B. A licensed pharmacist
C. A physician
D. The store manager
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:*
Pharmacy interns must have direct, on-site supervision by a licensed pharmacist to ensure
patient safety and legal compliance. </details>
5. A pharmacist's license expires on March 31 of even-numbered years. How many
continuing education (CE) hours are required for renewal?
A. 15 hours
B. 20 hours
C. 25 hours
D. 30 hours
<details> <summary>Answer & Rationale</summary> **Answer: D** *Rationale:* Illinois
requires 30 hours of continuing pharmacy education every 2 years. A waiver applies for the
first renewal after initial licensure. </details>
6. Of the 30 required CE hours for pharmacists in Illinois, how many must specifically be in
pharmacy law?
A. 0 hours
B. 1 hour
C. 2 hours
D. 5 hours
<details> <summary>Answer & Rationale</summary> **Answer: C** *Rationale:* While
Illinois generally does not dictate specific subjects (unlike some states), 2 hours must be
earned in pharmacy law. </details>
,Domain 3: Controlled Substances (CSA & Illinois Control Act)
7. A prescriber writes a prescription for Alprazolam 1mg (C-IV) with directions: "Refill x 6."
Under Illinois and Federal law, what should the pharmacist do?
A. Fill all 6 refills as written
B. Fill only 5 refills
C. Contact the DEA immediately
D. Refuse to fill the prescription entirely
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Federal
and Illinois law limit Schedule III, IV, and V refills to a maximum of 5 times within 6 months
of the issue date. The 6th refill is invalid. </details>
8. A patient presents a prescription for Oxycodone 5mg (C-II) dated April 1st. Today is June
15th (same year). Can this be filled?
A. Yes, C-II prescriptions are valid for 6 months
B. No, C-II prescriptions are only valid for 90 days
C. Yes, C-II prescriptions have no expiration date
D. No, C-II prescriptions are valid only for 7 days
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Schedule
II prescriptions are valid for only 90 days after the date issued. </details>
9. According to HB1638 (passed in 2025 for 2026), what is required when a person other
than the patient picks up a Schedule II controlled substance?
A. The person must sign a logbook visible to the public
B. The pharmacy must keep a photocopy of the pick-up person's photo ID for 90 days
C. The pick-up person must be a family member verified by a notary
D. No identification is required as long as the address matches
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* The new
2026 amendment to the Illinois Controlled Substances Act requires photo identification from
the person picking up the C-II, and the pharmacy must retain a copy in the file for 90
days[citation:2]. </details>
10. Which of the following is true regarding the sale of "Exempt Narcotics" (e.g., low-dose
codeine guaifenesin) in Illinois without a prescription?
A. It is prohibited under all circumstances
B. Only available to patients over 18 with a valid ID
C. Limited to 120mL/120g per person per 96-hour period
D. Must be stored behind the counter, but no record keeping is required
, <details> <summary>Answer & Rationale</summary> **Answer: C** *Rationale:* Illinois
law allows the sale of Schedule V exempt narcotics to persons over 21 (with 2 forms of ID),
limited to 4oz/120mL per 96 hours. </details>
Domain 4: Prescription & Dispensing Requirements
11. A physician issues three sequential 30-day prescriptions for a Schedule II stimulant
(Methylphenidate) all on the same day. Is this legal?
A. No, Schedule II prescriptions cannot be post-dated
B. Yes, provided the physician writes the earliest fill date on the 2nd and 3rd prescriptions
C. Yes, but only if the patient signs a waiver
D. No, Illinois limits C-II supplies to 30 days total
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Illinois
law allows up to a 90-day supply (3 sequential 30-day scripts) for C-IIs, provided the
prescriber writes the "earliest fill date" on the subsequent prescriptions. </details>
12. What is the required retention period for a written prescription for a non-controlled
legend drug (e.g., Amoxicillin) in Illinois?
A. 1 year
B. 2 years
C. 3 years
D. 5 years
<details> <summary>Answer & Rationale</summary> **Answer: C** *Rationale:* Illinois
law requires non-controlled prescription records to be kept for 3 years. </details>
13. A pharmacist receives an oral prescription for Hydrocodone/Acetaminophen 10/325mg
(C-II) from a prescriber for a patient in a Long-Term Care Facility (LTCF). May the
pharmacist dispense this?
A. No, oral C-II prescriptions are never allowed
B. Yes, but only for a 7-day supply, and a written prescription must follow in 7 days
C. Yes, but only if the pharmacist reduces it to writing and gets a fax first
D. No, the pharmacist must transfer the call to the DEA
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Federal
law allows oral C-II prescriptions for LTCF patients or for terminally ill patients, limited to a 7-
day supply, with a written copy to follow within 7 days. </details>
14. Which of the following is a valid "Do Not Substitute" (Brand Medically Necessary)
request in Illinois?
A. The patient requests the brand name verbally
B. The prescriber writes "Dispense as Written" (DAW) on the hard copy
Practice Questions And Correct Answers
(Verified Answers) Plus Rationales 2026 Q&A
| Instant Download |Verified Answers*
Illinois Pharmacy Law Examination (MPJE) Practice Exam
Domain 1: Licensure & Regulatory Authority
1. Which agency is primarily responsible for licensing pharmacists and enforcing the
Illinois Pharmacy Practice Act?
A. Illinois Department of Public Health (IDPH)
B. Drug Enforcement Administration (DEA)
C. Illinois Department of Financial and Professional Regulation (IDFPR)
D. Board of Pharmacy Specialties
<details> <summary>Answer & Rationale</summary> **Answer: C** *Rationale:* The
IDFPR, through the Division of Professional Regulation, oversees the licensure, registration,
and discipline of pharmacists and pharmacies in Illinois[citation:3]. </details>
2. According to a 2024 rule amendment effective January 1, 2026, what is required of a
Pharmacist-in-Charge (PIC) for an out-of-state (non-resident) pharmacy shipping into
Illinois?
A. Must visit the Illinois facility once per year
B. Must be licensed as a pharmacist in Illinois
C. Must hold a Doctor of Pharmacy degree
D. Must designate a local agent in Chicago
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:*
Specifically for 2026, the Illinois regulations (Ill. Admin. Code tit. 68, § 1330.550) mandate
that PICs of non-resident pharmacies must be licensed in Illinois, effective Jan 1, 2026.
</details>
,Domain 2: The Illinois Pharmacy Practice Act (PPA)
3. Under the Illinois Pharmacy Practice Act, what is required for a pharmacy technician to
practice in the state?
A. Certification by the PTCB only
B. Registration with the IDFPR
C. Completion of a 4-year degree
D. Direct employment by a hospital
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Illinois
law requires pharmacy technicians to be registered with the IDFPR. Certification (CPhT) is
required within two years of registration, but registration is the primary legal requirement.
</details>
4. A pharmacy intern in Illinois must practice under the direct supervision of:
A. A registered nurse
B. A licensed pharmacist
C. A physician
D. The store manager
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:*
Pharmacy interns must have direct, on-site supervision by a licensed pharmacist to ensure
patient safety and legal compliance. </details>
5. A pharmacist's license expires on March 31 of even-numbered years. How many
continuing education (CE) hours are required for renewal?
A. 15 hours
B. 20 hours
C. 25 hours
D. 30 hours
<details> <summary>Answer & Rationale</summary> **Answer: D** *Rationale:* Illinois
requires 30 hours of continuing pharmacy education every 2 years. A waiver applies for the
first renewal after initial licensure. </details>
6. Of the 30 required CE hours for pharmacists in Illinois, how many must specifically be in
pharmacy law?
A. 0 hours
B. 1 hour
C. 2 hours
D. 5 hours
<details> <summary>Answer & Rationale</summary> **Answer: C** *Rationale:* While
Illinois generally does not dictate specific subjects (unlike some states), 2 hours must be
earned in pharmacy law. </details>
,Domain 3: Controlled Substances (CSA & Illinois Control Act)
7. A prescriber writes a prescription for Alprazolam 1mg (C-IV) with directions: "Refill x 6."
Under Illinois and Federal law, what should the pharmacist do?
A. Fill all 6 refills as written
B. Fill only 5 refills
C. Contact the DEA immediately
D. Refuse to fill the prescription entirely
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Federal
and Illinois law limit Schedule III, IV, and V refills to a maximum of 5 times within 6 months
of the issue date. The 6th refill is invalid. </details>
8. A patient presents a prescription for Oxycodone 5mg (C-II) dated April 1st. Today is June
15th (same year). Can this be filled?
A. Yes, C-II prescriptions are valid for 6 months
B. No, C-II prescriptions are only valid for 90 days
C. Yes, C-II prescriptions have no expiration date
D. No, C-II prescriptions are valid only for 7 days
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Schedule
II prescriptions are valid for only 90 days after the date issued. </details>
9. According to HB1638 (passed in 2025 for 2026), what is required when a person other
than the patient picks up a Schedule II controlled substance?
A. The person must sign a logbook visible to the public
B. The pharmacy must keep a photocopy of the pick-up person's photo ID for 90 days
C. The pick-up person must be a family member verified by a notary
D. No identification is required as long as the address matches
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* The new
2026 amendment to the Illinois Controlled Substances Act requires photo identification from
the person picking up the C-II, and the pharmacy must retain a copy in the file for 90
days[citation:2]. </details>
10. Which of the following is true regarding the sale of "Exempt Narcotics" (e.g., low-dose
codeine guaifenesin) in Illinois without a prescription?
A. It is prohibited under all circumstances
B. Only available to patients over 18 with a valid ID
C. Limited to 120mL/120g per person per 96-hour period
D. Must be stored behind the counter, but no record keeping is required
, <details> <summary>Answer & Rationale</summary> **Answer: C** *Rationale:* Illinois
law allows the sale of Schedule V exempt narcotics to persons over 21 (with 2 forms of ID),
limited to 4oz/120mL per 96 hours. </details>
Domain 4: Prescription & Dispensing Requirements
11. A physician issues three sequential 30-day prescriptions for a Schedule II stimulant
(Methylphenidate) all on the same day. Is this legal?
A. No, Schedule II prescriptions cannot be post-dated
B. Yes, provided the physician writes the earliest fill date on the 2nd and 3rd prescriptions
C. Yes, but only if the patient signs a waiver
D. No, Illinois limits C-II supplies to 30 days total
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Illinois
law allows up to a 90-day supply (3 sequential 30-day scripts) for C-IIs, provided the
prescriber writes the "earliest fill date" on the subsequent prescriptions. </details>
12. What is the required retention period for a written prescription for a non-controlled
legend drug (e.g., Amoxicillin) in Illinois?
A. 1 year
B. 2 years
C. 3 years
D. 5 years
<details> <summary>Answer & Rationale</summary> **Answer: C** *Rationale:* Illinois
law requires non-controlled prescription records to be kept for 3 years. </details>
13. A pharmacist receives an oral prescription for Hydrocodone/Acetaminophen 10/325mg
(C-II) from a prescriber for a patient in a Long-Term Care Facility (LTCF). May the
pharmacist dispense this?
A. No, oral C-II prescriptions are never allowed
B. Yes, but only for a 7-day supply, and a written prescription must follow in 7 days
C. Yes, but only if the pharmacist reduces it to writing and gets a fax first
D. No, the pharmacist must transfer the call to the DEA
<details> <summary>Answer & Rationale</summary> **Answer: B** *Rationale:* Federal
law allows oral C-II prescriptions for LTCF patients or for terminally ill patients, limited to a 7-
day supply, with a written copy to follow within 7 days. </details>
14. Which of the following is a valid "Do Not Substitute" (Brand Medically Necessary)
request in Illinois?
A. The patient requests the brand name verbally
B. The prescriber writes "Dispense as Written" (DAW) on the hard copy
