MCB 410 Quiz #2 UPDATED ACTUAL Questions and CORRECT
Answers
Proteins that are fully translated in the cytosol do NOT -the golgi
end up in
-the cytosol
-the interior of the nucleus
-the golgi
-the mitochondria
Which of the following membrane lipids does not contain -cholesterol
a fatty acid tail?
-a glycolipid
-phosphatidylcholine
-cholesterol
-phosphatidylserine
Glycolipids -can be recognized by specific antibodies
-are found only in the endoplasmic reticulum
-are mostly on the cytosolic face of the plasma
membrane
-are not medically relevant
-can be recognized by specific antibodies
According to Figure 12-18 in Essential Cell Biology, 5th ed. -higher, higher
ATP-driven pumps in animal cells lead to a _______
concentration of Na+ ions outside the cell compared to
inside the cell, and a ___ concentration of H+ ions in the
lysosome relative to the cytosol.
-higher, lower
-lower, lower
-higher, higher
-lower, higher
After isolating the rough endoplasmic reticulum from he -all of the answers are correct
rest of the cytoplasm, you purify the RNAs attached to it.
Which of the following proteins fo you expect the RNA
from the rough endoplasmic reticulum to encode?
-soluble secreted proteins
-ER membrane proteins
-plasma membrane proteins
-all of the answers are correct
, Pumps are transporters that are able to harness energy -active transport
provided by other components in cells to drive the
movement of solutes across membranes against their
concentration gradient. This type of transport is called...
-active transport
-free diffusion
-facillated diffusion
-passive transport
The phosphorylation of a protein is typically associated -protein degradation
with a change in activity, the assembly of a protein
complex, or the triggering of a downstream signaling
cascade. The addition of ubiquitin, a small polypeptide, is
another type of covalent modification that can affect
protein function. Ubiquitylation often results in:
-protein degradation
-nuclear translocation
-membrane association
-protein secretion
We know the detailed molecular structure and -H+
mechanism of action of the transmembrane protein
bacteriothosopsin. The protein uses sunlight as the
source of energy to pump __ out of the cell.
-H+
-Na+
-ATP
-K+
Some cells express aquaporin proteins—they are channel -solute concentrations on either side of the membrane
proteins that facilitate the flow of water molecules
through the plasma membrane. What regulates the rate
and direction of water diffusion across the membrane?
-aquaporin conformation
-solute concentrations on either side of the membrane
-availability of ATP
-resting membrane potential
Which statement best describes the hypothesis that -Treatment of cells with both a corrector and a proteasome inhibitor leads to
Chung et al (2016) tested in their experiments with the increased levels of D F508 CFTR in the plasma membrane
DeltaF508 CFTR mutant?
-Treatment of cells with both a corrector and a
proteasome inhibitor leads to increased levels of D F508
CFTR in the plasma membrane
-The CFTR Cl- channel opens less frequently in response
to the CFTR corrector C18
-Gylcosylation of the CFTR protein is inhibited by the
proteasome
-The D F508 mutation decreases CFTR co-translational
import into the ER
Answers
Proteins that are fully translated in the cytosol do NOT -the golgi
end up in
-the cytosol
-the interior of the nucleus
-the golgi
-the mitochondria
Which of the following membrane lipids does not contain -cholesterol
a fatty acid tail?
-a glycolipid
-phosphatidylcholine
-cholesterol
-phosphatidylserine
Glycolipids -can be recognized by specific antibodies
-are found only in the endoplasmic reticulum
-are mostly on the cytosolic face of the plasma
membrane
-are not medically relevant
-can be recognized by specific antibodies
According to Figure 12-18 in Essential Cell Biology, 5th ed. -higher, higher
ATP-driven pumps in animal cells lead to a _______
concentration of Na+ ions outside the cell compared to
inside the cell, and a ___ concentration of H+ ions in the
lysosome relative to the cytosol.
-higher, lower
-lower, lower
-higher, higher
-lower, higher
After isolating the rough endoplasmic reticulum from he -all of the answers are correct
rest of the cytoplasm, you purify the RNAs attached to it.
Which of the following proteins fo you expect the RNA
from the rough endoplasmic reticulum to encode?
-soluble secreted proteins
-ER membrane proteins
-plasma membrane proteins
-all of the answers are correct
, Pumps are transporters that are able to harness energy -active transport
provided by other components in cells to drive the
movement of solutes across membranes against their
concentration gradient. This type of transport is called...
-active transport
-free diffusion
-facillated diffusion
-passive transport
The phosphorylation of a protein is typically associated -protein degradation
with a change in activity, the assembly of a protein
complex, or the triggering of a downstream signaling
cascade. The addition of ubiquitin, a small polypeptide, is
another type of covalent modification that can affect
protein function. Ubiquitylation often results in:
-protein degradation
-nuclear translocation
-membrane association
-protein secretion
We know the detailed molecular structure and -H+
mechanism of action of the transmembrane protein
bacteriothosopsin. The protein uses sunlight as the
source of energy to pump __ out of the cell.
-H+
-Na+
-ATP
-K+
Some cells express aquaporin proteins—they are channel -solute concentrations on either side of the membrane
proteins that facilitate the flow of water molecules
through the plasma membrane. What regulates the rate
and direction of water diffusion across the membrane?
-aquaporin conformation
-solute concentrations on either side of the membrane
-availability of ATP
-resting membrane potential
Which statement best describes the hypothesis that -Treatment of cells with both a corrector and a proteasome inhibitor leads to
Chung et al (2016) tested in their experiments with the increased levels of D F508 CFTR in the plasma membrane
DeltaF508 CFTR mutant?
-Treatment of cells with both a corrector and a
proteasome inhibitor leads to increased levels of D F508
CFTR in the plasma membrane
-The CFTR Cl- channel opens less frequently in response
to the CFTR corrector C18
-Gylcosylation of the CFTR protein is inhibited by the
proteasome
-The D F508 mutation decreases CFTR co-translational
import into the ER
