Immunocompetence
the ability of the body to produce a normal immune
response when exposed to an antigen
immunosuppression
a condition where the immune system is weakened and
less able to fight off infections and disease
immunodeficiency
a condition where the immune system is unable to fight
infections
What are the four types of hypersensitivity reactions
- Type 1 immediate hypersensitivity
-type 2 cytotoxic hypersensitivity
-type 3 immune complex disorders
-type 4 delayed hypersensitivity
,Type 1 immediate hypersensitivity
a rapidly developing immune reaction that occurs after
IgE binds to mast cells and combines with antigen.
symptoms of a type 1 immediate hypersensitivity
anaphylaxis, angioedema, allergic rhinitis, urticaria,
allergy or atopic disorder.
Type 2 cytotoxic hypersensitivity
is mediated by Igs directed toward antigens present on
cell surfaces.
What type of hypersensitivity reaction is caused by a
transfusion reaction
type 2 cytotoxic hypersensitivity
type 3 immune complex hypersensitivity
,occurs when antigen combines with IG within circulation
and these complexes are then deposited in the tissue
What type of hypersensitivity is RA and SLE
Type 3 immune complex hypersensitivity
Type 4 delayed hypersensitivity
is initiated by t lymphocytes that have had previous
exposure to antigen
what are the type 4 delayed hypersensitivity reactions
Positive PPD test
poison ivy
organ transfusion rejection
what happens during a transfusion reaction
The donor anti Igs of the recipient will attack and destroy
the hosts red blood cells causing a massive hemolytic
reactions.
, Pathological changes in white blood cells with infection
increase number of immature white blood cells in the
blood
Key lab values in infection
elevate IgG and IgM, WBC, neutrophils
bacterial infection lab results
elevated WBC with elevated neutrophils
viral infection lab results
elevated WBC with elevated lymphocytes
Hypervolemia
abnormal increase in the volume of blood plasma in the
body