NU553 Unit 3 Parkinsons Disease Advanced
Pharmacology and Pharmacotherapeutics
Exam 2 UPDATED ACTUAL Questions and
CORRECT Answers
Please check out my other flash card decks for help with your exams in Purdue Globals NU553 and
prepare for Board Certification. - CORRECT ANSWER Ok!
What is the mean age of onset for Parkinson’s disease? - CORRECT ANSWER 65 years
What is the male to female ratio for Parkinson’s disease? - CORRECT ANSWER 1.4 to 1
Which brain region degenerates in Parkinson’s disease? - CORRECT ANSWER Substantia
nigra pars compacta
What percentage of dopaminergic neurons are lost at diagnosis? - CORRECT ANSWER At least 50
percent
What are Lewy bodies composed of? - CORRECT ANSWER Alpha synuclein and ubiquitin
What is required for diagnosis of parkinsonism? - CORRECT ANSWER Bradykinesia plus tremor
rigidity or both
List the four cardinal motor symptoms of Parkinson’s disease. - CORRECT
ANSWER Bradykinesia resting tremor rigidity postural instability
What environmental exposure increases Parkinson’s disease risk? - CORRECT
ANSWER Chronic pesticide exposure
, Are tobacco and caffeine protective for Parkinson’s disease? - CORRECT ANSWER TRUE
Drug-induced parkinsonism is typically what after stopping the drug? - CORRECT
ANSWER Reversible
Most common cause of drug-induced parkinsonism? - CORRECT ANSWER First generation
antipsychotics
Which antipsychotics have lowest risk of drug-induced parkinsonism? - CORRECT
ANSWER Clozapine and quetiapine
Which gastrointestinal drug can cause drug-induced parkinsonism? - CORRECT
ANSWER Metoclopramide
Which antiepileptic drug can cause drug-induced parkinsonism? - CORRECT ANSWER Valproic
acid
How long can drug-induced parkinsonism take to resolve? - CORRECT ANSWER Up to 2 years
What imaging differentiates Parkinson’s disease from drug-induced parkinsonism? - CORRECT
ANSWER Dopamine transporter imaging
What is the goal of Parkinson’s disease treatment? - CORRECT ANSWER Improve quality of
life and symptoms
Which scale monitors Parkinson’s disease progression? - CORRECT ANSWER Unified
Parkinson’s Disease Rating Scale
Anticholinergics are best for which symptoms? - CORRECT ANSWER Tremor and drooling
Pharmacology and Pharmacotherapeutics
Exam 2 UPDATED ACTUAL Questions and
CORRECT Answers
Please check out my other flash card decks for help with your exams in Purdue Globals NU553 and
prepare for Board Certification. - CORRECT ANSWER Ok!
What is the mean age of onset for Parkinson’s disease? - CORRECT ANSWER 65 years
What is the male to female ratio for Parkinson’s disease? - CORRECT ANSWER 1.4 to 1
Which brain region degenerates in Parkinson’s disease? - CORRECT ANSWER Substantia
nigra pars compacta
What percentage of dopaminergic neurons are lost at diagnosis? - CORRECT ANSWER At least 50
percent
What are Lewy bodies composed of? - CORRECT ANSWER Alpha synuclein and ubiquitin
What is required for diagnosis of parkinsonism? - CORRECT ANSWER Bradykinesia plus tremor
rigidity or both
List the four cardinal motor symptoms of Parkinson’s disease. - CORRECT
ANSWER Bradykinesia resting tremor rigidity postural instability
What environmental exposure increases Parkinson’s disease risk? - CORRECT
ANSWER Chronic pesticide exposure
, Are tobacco and caffeine protective for Parkinson’s disease? - CORRECT ANSWER TRUE
Drug-induced parkinsonism is typically what after stopping the drug? - CORRECT
ANSWER Reversible
Most common cause of drug-induced parkinsonism? - CORRECT ANSWER First generation
antipsychotics
Which antipsychotics have lowest risk of drug-induced parkinsonism? - CORRECT
ANSWER Clozapine and quetiapine
Which gastrointestinal drug can cause drug-induced parkinsonism? - CORRECT
ANSWER Metoclopramide
Which antiepileptic drug can cause drug-induced parkinsonism? - CORRECT ANSWER Valproic
acid
How long can drug-induced parkinsonism take to resolve? - CORRECT ANSWER Up to 2 years
What imaging differentiates Parkinson’s disease from drug-induced parkinsonism? - CORRECT
ANSWER Dopamine transporter imaging
What is the goal of Parkinson’s disease treatment? - CORRECT ANSWER Improve quality of
life and symptoms
Which scale monitors Parkinson’s disease progression? - CORRECT ANSWER Unified
Parkinson’s Disease Rating Scale
Anticholinergics are best for which symptoms? - CORRECT ANSWER Tremor and drooling
