CORRECT Answers
, Class I Antiarrhythmics Sodium channel blockers that slow conduction (e.g., Quinidine, Lidocaine,
Flecainide).
Class II Antiarrhythmics Beta blockers that reduce heart rate and AV conduction (e.g., Metoprolol,
Propranolol).
Class III Antiarrhythmics Potassium channel blockers that prolong repolarization (e.g., Amiodarone,
Sotalol).
Class IV Antiarrhythmics Calcium channel blockers that slow AV node conduction (e.g., Diltiazem,
Verapamil).
Amiodarone Monitoring Monitor for pulmonary toxicity, thyroid dysfunction, and liver function
abnormalities.
Statins MOA Inhibit HMG-CoA reductase → ↓ cholesterol synthesis; increases LDL receptor
expression.
ACE Inhibitors Adverse Effect Cough and angioedema due to bradykinin accumulation; contraindicated in
pregnancy.
ARB MOA Block angiotensin II receptor → ↓ vasoconstriction and aldosterone secretion.
Thiazide Diuretics Inhibit NaI reabsorption in distal tubule; can cause hypokalemia and
hyperuricemia.
Beta Blocker Contraindication Avoid in asthma/COPD due to bronchospasm risk.
Nitrate Mechanism Release nitric oxide → venodilation → ↓ preload and myocardial OI demand.
Digoxin Toxicity Signs Nausea, visual halos, arrhythmias; worsened by hypokalemia.
Warfarin MOA Vitamin K antagonist inhibiting synthesis of clotting factors II, VII, IX, X.
Warfarin Monitoring Monitor INR (goal 2-3); adjust for diet and drug interactions.
DOAC Examples Rivaroxaban, Apixaban (Xa inhibitors), Dabigatran (direct thrombin inhibitor).
Iron Deficiency Anemia Labs ↓Ferritin, ↑TIBC, ↓Hgb; treat with oral ferrous sulfate 325 mg TID.
Vitamin B12 Deficiency Macrocytic anemia with neurologic symptoms; treat with IM cyanocobalamin.
Folate Deficiency Macrocytic anemia without neurologic changes; treat with oral folic acid.
Asthma Step 1 SABA as needed (e.g., Albuterol).
Asthma Step 2 Low-dose ICS (Fluticasone).
Asthma Step 3 Low-dose ICS + LABA (e.g., Fluticasone + Salmeterol).
Asthma Step 5 High-dose ICS + LABA + specialist referral.