NR 507 WEEK 5 EDAPT; DEPRESSION | QUESTIONS AND ANSWERS | 2026 UPDATED | 100% CORRECT - CHAMBERLAIN COLLEGE OF NURSING

,
, NR 507 WEEK 5 EDAPT; DEPRESSION |
QUESTIONS AND ANSWERS | 2026
UPDATED | 100% CORRECT -
CHAMBERLAIN COLLEGE OF NURSING.



Section 1: Pathophysiology & Neurotransmitter
Theories (Questions 1-15)
Question 1: What is the underlying basis of depression according to
the Monoamine Deficiency Theory?

A) Elevated levels of serotonin and norepinephrine in the synaptic cleft
B) Deficiency (low levels) of serotonin, norepinephrine, and dopamine
C) Excessive reuptake of acetylcholine
D) Overactive glutamate receptors in the prefrontal cortex

Answer: B – Deficiency (low levels) of serotonin, norepinephrine, and
dopamine

Rationale: The Monoamine Deficiency Theory indicates that the underlying
basis of depression is low levels of serotonin, norepinephrine, and
dopamine . These neurotransmitters are known collectively as monoamines
because they have one amine group. This theory is supported by the
effectiveness of SSRIs and SNRIs, which increase the availability of these
neurotransmitters in the synapse .




Question 2: Which neurotransmitters are primarily implicated in the
pathophysiology of major depressive disorder?

A) GABA and glutamate only
B) Acetylcholine and histamine only
C) Serotonin, norepinephrine, and dopamine
D) Epinephrine and cortisol only