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PHCH 667 EXAM 3 QUIZ QUESTIONS AND ANSWERS

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PHCH 667 EXAM 3 QUIZ QUESTIONS AND ANSWERS

Institution
PHCH 667
Course
PHCH 667

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Which of the following markers typically requires testing of biopsied material rather than
serum?
A. CEA
B. CA19-9
C. CA 125
D. HER-2


Give this one a go later!


D. HER-2




A cancer patient is about to initiate chemotherapy with irinotecan. You are informed that
this patient has been previously genotypes for UGT1A1, CYP2CP, CYP2D6. What should
be your course of action when you learned about genotyping results?
A. Only consider UGT1A1 genotype. If the patient is homozygous for *28 variants, starting

,dose should be decreased at least one level as recommended by the FDA, regardless of
other UGT1A1 variants.
B. Consider all genotype information. If the patient is homozygous for a variant of any
one of the three enzymes, starting dose should be decreased at least one level as
recommended by the FDA
C. Disregard the genotype information since the FDA has not included genotyping
information to the irinotecan drug label
D. Only consider UGT1A1 genotype. If the patient is homozygous for either of the 28, 6,
27, 29, or *7 variants, starting dose should be decreased at least one level as recommend


Give this one a go later!


A. Only consider UGT1A1 genotype. If the patient is homozygous for *28
variants, starting dose should be decreased at least one level as
recommended by the FDA, regardless of other UGT1A1 variants.




Which online resource curates the latest information on drug labels with PGx information
and on genetic tests for PGx?
A. Wikipedia
B. Pubmed
C. Google
D. PharmGKB.org


Give this one a go later!


D. PharmGKB.org




What is the function of thyroid hormone?
A) Solely regulate reproductive processes
B) Inhibit secretion of growth hormone

, C) Maintain water homeostasis
D) Regulate carbohydrate, lipid, and protein metabolism within cells


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D) Regulate carbohydrate, lipid, and protein metabolism within cells




A disorder of the thyroid caused by autoimmune reaction to TSH receptor is _________?
A) Euthyroid disease
B) Hashimoto's thyroiditis
C) Sick euthyroid syndrome
D) Grave's disease


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D) Grave's disease




The normal role of PSA is what?
A. liquefy semen to promote the swimming movements of sperm
B. promote growth of epithelial cells in the prostate
C. cleave alpha-2-macroglobulin in the blood
D. bind and activate anti-chymotrypsin in the blood


Give this one a go later!


A. liquefy semen to promote the swimming movements of sperm

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Institution
PHCH 667
Course
PHCH 667

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