ACTUAL EXAM 2026/2027 | NC Funeral
Director Pathology | Verified Q&A | Pass
Guaranteed - A+ Graded
Section 1: Pathological Processes & Disease Classifications
Q1: Which type of necrosis is most characteristic of ischemic injury to the brain, resulting in the
transformation of tissue into a liquid viscous mass?
A. Coagulative necrosis.
B. Caseous necrosis.
C. Liquefactive necrosis. [CORRECT]
D. Fat necrosis.
Correct Answer: C
Rationale: Liquefactive necrosis occurs when enzymatic digestion dissolves the tissue, typical in the
brain due to its high lipid content and lack of connective tissue framework. Coagulative necrosis
preserves the tissue outline (typical in heart/kidney), while Caseous resembles cheese (typical in
tuberculosis). Embalming implication: Brain tissue loss may require cavity packing or restorative
measures if autopsied.
Q2: A deceased individual has a history of advanced tuberculosis. Autopsy reveals cheese-like, white
debris in the lungs. This finding is pathognomonic for which type of necrosis?
A. Coagulative necrosis.
B. Caseous necrosis. [CORRECT]
C. Fat necrosis.
D. Fibrinoid necrosis.
,Correct Answer: B
Rationale: Caseous necrosis ("cheesy" appearance) is distinctively associated with tuberculosis
infections. It is a combination of coagulative and liquefactive processes. Coagulative necrosis is seen in
solid organs; Fat necrosis is seen in pancreatic disease or breast trauma.
Q3: During an autopsy, the pathologist notes a "dystrophic calcification" in a damaged heart valve. This
process is defined as:
A. Calcium deposition in normal tissues due to hypercalcemia.
B. Calcium deposition in areas of tissue necrosis or degeneration with normal serum calcium levels.
[CORRECT]
C. Metastatic spread of a primary cardiac tumor.
D. Hemorrhage into the valve leaflets.
Correct Answer: B
Rationale: Dystrophic calcification occurs in damaged or necrotic tissue despite normal blood calcium
levels, often seen in atherosclerotic plaques or damaged heart valves. Metastatic calcification (Option A)
occurs in normal tissues due to high serum calcium.
Q4: "Metastasis" refers specifically to:
A. The uncontrolled growth of cells within a single tissue.
B. The spread of malignant cells from a primary site to a distant site. [CORRECT]
C. The transformation of a benign tumor into a malignant one.
D. The formation of new blood vessels within a tumor.
Correct Answer: B
Rationale: Metastasis is the hallmark of malignancy, defining the ability of cancer cells to invade and
colonize distant organs. Benign tumors do not metastasize. Angiogenesis (Option D) supports growth
but is not the spread itself.
Q5: Which term describes an accumulation of fluid in tissues, resulting in swelling, often visible as
"pitting" edema in the extremities?
,A. Hemorrhage.
B. Thrombosis.
C. Edema. [CORRECT]
D. Embolism.
Correct Answer: C
Rationale: Edema is the accumulation of fluid in interstitial tissues. Hemorrhage is blood loss;
Thrombosis is a clot; Embolism is a traveling obstruction. Embalming implication: Edematous tissues
require higher fluid index or massage to reduce swelling (antiedema chemicals).
Q6: A "thrombus" differs from an "embolus" in that a thrombus is:
A. Always composed of air.
B. A mass of bacterial origin.
C. A clot attached to the vessel wall at its site of origin. [CORRECT]
D. A traveling mass that has moved from its origin.
Correct Answer: B
Rationale: A thrombus is a stationary clot attached to the vessel wall. An embolus is a detached mass
(clot, fat, air, bacteria) that travels through the bloodstream. A thrombus can become an embolus if it
breaks free.
Q7: An area of ischemic necrosis in a solid organ like the kidney or spleen is termed a(n):
A. Infarct. [CORRECT]
B. Abscess.
C. Ulcer.
D. Gangrene.
Correct Answer: B
Rationale: An infarct is an area of tissue death (necrosis) caused by obstruction of blood supply
(ischemia). An abscess is a localized infection; an ulcer is a loss of surface epithelium; gangrene is
necrosis involving putrefaction.
, Q8: "Hyperplasia" is best defined as:
A. An increase in the size of individual cells.
B. An increase in the number of cells in a tissue. [CORRECT]
C. A decrease in the size of cells.
D. A change in cell type to another mature cell type.
Correct Answer: B
Rationale: Hyperplasia is an increase in cell number (e.g., prostate enlargement). Hypertrophy (Option
A) is an increase in cell size (e.g., heart muscle in hypertension). Atrophy is decrease in size; Metaplasia
is change in cell type.
Q9: During the inflammatory response, the accumulation of pus composed of neutrophils, fluid, and
cellular debris is known as:
A. Serous exudate.
B. Fibrinous exudate.
C. Purulent exudate. [CORRECT]
D. Hemorrhagic exudate.
Correct Answer: B
Rationale: Purulent exudate (pus) indicates a bacterial infection. Serous exudate is clear/watery (e.g.,
blister fluid). Fibrinous exudate has high fibrin content (seen in pericarditis). Hemorrhagic exudate
contains blood.
Q10: "Apoptosis" refers to:
A. Accidental cell death due to injury.
B. Programmed cell death. [CORRECT]
C. Swelling of the cell due to fluid intake.
D. Necrosis caused by toxins.