NR 546 psychopharmacology midterm EXAM A+ GRADE ASSURED COMPLETE SOLUTIONS AND VERIFIED ANSWERS

EXAM

Exam Solutionms




NR546 psychopharmacology Final exam 2026 A+ GRA
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DE ASSURED COMPLETE SOLUTIONS AND VERIFIED AN
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SWERS (66859) ms




QUESTION 1 ms




monoamine hypothesis of depression ms ms ms




ANSWER

depression occurs as a result of deficiency of 1 or all 3 monoamine NT -
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occurs due to too little positive affect or too much negative affect (mania will occur from excess of
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all 3)
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QUESTION 2 ms




what are the three monoamine NT
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ANSWER

NE, DA, 5HT
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QUESTION 3 ms




too little positive affect
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ANSWER

-DA/NE dysfunction -DA levels low = loss of pleasure, interest, alertness, self-confidence -
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DA levels high = hallucinations seen in schizo -
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NE (fight or flight) high = antsy, nervous, affects focus ability -
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depressed mood, loss of joy, lack of interest, loss of energy, decreased alertness, decreased self-
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confidence, appetite changes ms ms




QUESTION 4 ms




too much negative affect
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,ANSWER

-
5HT = relaxation, comfort, decreases stress, regulates libido, arousal, sleep, aggression, pain percepti
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on -5HT/NE dysfunction -
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depressed mood, guilt, fear/anxiety, hostility, irritability, loneliness, appetite changes
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QUESTION 5 ms




prescribing considerations ms




ANSWER

-client preference -prior treatment response -anticipated adverse effects -comorbidities -half-
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life interactions -cost
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QUESTION 6 ms




client preference ms




ANSWER

if no contraindication, then prescribe that med to improve adherence
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QUESTION 7 ms




prior treatment response
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ANSWER

if patient had success with a previous med, prescribe that one first
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QUESTION 8 ms




anticipated adverse events ms ms




ANSWER

-consider age, family planning, and anticipated adverse effects. -
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use adverse effects to pt's advantage (choose a known activating medication for a pt with atypical d
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epression or choose a sedating medication for a patient with sleep disturbances)
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QUESTION 9 ms




Comorbidities
ANSWER

,clients with comorbid anxiety may experience worsening symptoms when taking medications that ta
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rget NE (SNRIs) -
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fluoxetine is known to activate clients and cause panic attacks in clients with comorbid anxiety
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QUESTION 10 ms




half-life interactions ms




ANSWER

-
choose a medication with a longer half life to avoid discontinuation syndrome if your client forgets t
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o take it -
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many antidepressants have significant interactions with other meds due to CYP450 enzyme involvem
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ent



QUESTION 11 ms




cost
ANSWER

if client cant afford medication, they will not benefit. keep cost, insurance benefits, and pharmaceutic
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al assistance programs in mind
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QUESTION 12 ms




goal of antidepressant medications
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ANSWER

complete remission of symptoms
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QUESTION 13 ms




antidepressant prescribing schedule ms ms




ANSWER

-start on a single drug for 4-8 weeks -
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if not working: 1. increase dose gradually until efficacy occurs 2. switch to different drug within sam
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e drug class after adequate trial which included higher dosing and a minimum of 8 weeks 3. switch
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to a drug in a different class after adequate trial and higher dosing 4. add a second med as adjunct
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QUESTION 14 ms




SSRI MOA ms

, ANSWER

inhibit 5HT reuptake first line of treatment for depression
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QUESTION 15 ms




SSRI s/e ms




ANSWER

7 S's of SSRIs 1. Stomach 2. sexual dysfunction 3. serotonin syndrome 4. sleep difficulties 5. suicidal
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thoughts 6. stress 7. size (weight)
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QUESTION 16 ms




serotonin s/e ms




ANSWER

head, red, fed head = decreased anxiety, impulsivity, sex drive red = platelets and bleeding fed = gi
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motility and nausea ms ms




QUESTION 17 ms




SSRI pt education
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ANSWER

most adverse affects will subside after 4-5 days once body adjusts to increased serotonin levels
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QUESTION 18 ms




SSRI drugs ms




ANSWER

citalopram fluoxetine paroxetine sertraline fluvoxamine bupropion
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QUESTION 19 ms




citalopram
ANSWER

*has a mild antihistamine effect *causes QT prolongation citalopram = celexa, think of cel LEXUS (ca
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r) = car - get an electrocardiogram if on this drug
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QUESTION 20 ms