MICB 212 CERTIFICATION PAPER 2026
FULL SOLUTION GRADED A+
● two major cell populations in blood?. Answer: 1) erythrocytes (also
called red blood cells or RBCs) carry oxygen to the tissues,
2) leukocytes (also called white blood cells or WBCs) are the cells of the
immune system.
● Do ALL blood cells, including RBCs, arise from hematopoietic stem
cells?. Answer: YES including RBCs
● hematopoetic stem cells. Answer: -self-renewing stem cells,
-found in the bone marrow, umbilical cord blood and in the blood (a
very small number).
● leukocytes. Answer: myeloid and lymphoid cells
● myeloid cells. Answer: Participate in the INNATE immune response
-monocytes (that mature into macrophages),
,-mast cells,
-granulocytes (neutrophils, basophils, and eosinophils).
● Lymphoid cells (aka lymphocytes). Answer: Participate in the
ADAPTIVE immune response
-cytotoxic T cells (CTLs),
-T helper (Th) cells,
-T regulatory (Treg) cells,
-B cells.
Natural killer cells (NK cells) - type of lymphoid cell that participates in
innate responses. not be discussed in MICB 202.
● dendritic cells. Answer: Dendritic cells - integral links between the
innate and adaptive responses.
,important cells for activating T cells & initiating adaptive immune
response.
some come from myeloid others from lymphoid
● location of immune system cells. Answer: The cells of the immune
system are found in the:
-blood circulatory system,
-lymphatic circulatory system,
-lymphoid organs.
● Primary lymphoid organs. Answer: site where lymphocytes mature
Primary lymphoid organs:
1) bone marrow
2 Thymus
, ● do all hematopoetic cells differentiate and mature in bone marrow.
Answer: ALL EXCEPT T cells (T cells begin in bone marrow and finish
in thymus)
● Secondary lymphoid organs. Answer: where mature lymphocytes
encounter pathogens or foreign molecules and where adaptive immune
responses begin
The secondary lymphoid organs include:
1) the spleen
2) the lymph nodes (located throughout the body).
lymph similar to blood but has no RBCs or platelets
● lymph-blood circulatory system pathway?. Answer: tissue -> lymph
capillaries -> lymph nodes -> blood (via thoracic duct)
● What are the differences between the primary and secondary lymphoid
organs?. Answer: primary lymphoid organ - where lymphocytes develop
and mature,
FULL SOLUTION GRADED A+
● two major cell populations in blood?. Answer: 1) erythrocytes (also
called red blood cells or RBCs) carry oxygen to the tissues,
2) leukocytes (also called white blood cells or WBCs) are the cells of the
immune system.
● Do ALL blood cells, including RBCs, arise from hematopoietic stem
cells?. Answer: YES including RBCs
● hematopoetic stem cells. Answer: -self-renewing stem cells,
-found in the bone marrow, umbilical cord blood and in the blood (a
very small number).
● leukocytes. Answer: myeloid and lymphoid cells
● myeloid cells. Answer: Participate in the INNATE immune response
-monocytes (that mature into macrophages),
,-mast cells,
-granulocytes (neutrophils, basophils, and eosinophils).
● Lymphoid cells (aka lymphocytes). Answer: Participate in the
ADAPTIVE immune response
-cytotoxic T cells (CTLs),
-T helper (Th) cells,
-T regulatory (Treg) cells,
-B cells.
Natural killer cells (NK cells) - type of lymphoid cell that participates in
innate responses. not be discussed in MICB 202.
● dendritic cells. Answer: Dendritic cells - integral links between the
innate and adaptive responses.
,important cells for activating T cells & initiating adaptive immune
response.
some come from myeloid others from lymphoid
● location of immune system cells. Answer: The cells of the immune
system are found in the:
-blood circulatory system,
-lymphatic circulatory system,
-lymphoid organs.
● Primary lymphoid organs. Answer: site where lymphocytes mature
Primary lymphoid organs:
1) bone marrow
2 Thymus
, ● do all hematopoetic cells differentiate and mature in bone marrow.
Answer: ALL EXCEPT T cells (T cells begin in bone marrow and finish
in thymus)
● Secondary lymphoid organs. Answer: where mature lymphocytes
encounter pathogens or foreign molecules and where adaptive immune
responses begin
The secondary lymphoid organs include:
1) the spleen
2) the lymph nodes (located throughout the body).
lymph similar to blood but has no RBCs or platelets
● lymph-blood circulatory system pathway?. Answer: tissue -> lymph
capillaries -> lymph nodes -> blood (via thoracic duct)
● What are the differences between the primary and secondary lymphoid
organs?. Answer: primary lymphoid organ - where lymphocytes develop
and mature,
