PRACTICE SOLUTIONS GRADED A+
● helical, icosahedral or complex. Answer: What are the 3 types of
morphology capsids can have?
● cross reactivity. Answer: antibodies against the bacteria cross-react
with structures in the host and cause damage
● effectiveness. Answer: when a study is carried out less than perfectly
controlled conditions
● efficacy. Answer: when a study is carried out under ideal conditions
such as a clinical trial
● 1. Abortive polio
2. Non-paralytic polio
3. Paralytic polio
4. Subclinical infection with no symptoms
5. PPMA (years after infection AND recovery only). Answer: Name the
5 possible responses after infection with poliovirus?
, ● post poliomyelitis muscle atrophy (PPMA). Answer: What does
PPMA stand for?
● aseptic meningitis. Answer: Non-paralytic poliomyelitis is also
referred to as?
● Serotype. Answer: variant of a virus that will elicit the production of
distinct population of antibodies
● Inactivated Poliovirus Vaccine (IPV) is injected.
Oral Poliovirus Vaccine (OPV) is given orally as a syrup.. Answer: What
types of poliovirus vaccines are available and how are they
administered?
● 1. Immunity in blood when given in sufficient dose
2. Uses inactivated virus so it can be used with immunodeficient
individuals
3. No reversion of virus to virulent form by mutation. Answer: List 3
advantages of IPV (Salk's) vaccine
● 1. Requires booster every 5 years
2. No IgA secretion so vaccinated people can still get gut infection
3. Vx person can still infect other by oral fecal route