This PNP301 (Pathophysiology for the Practical Nurse I) Test 3 typically covers complex
body systems and clinical conditions, specifically focusing on Hematologic System
Disorders, Endocrinology, and Shock. This exam assessment validates a student's ability
to link clinical manifestations with underlying pathophysiological processes in a systems-
based format.
Key Topics Covered in Test 3
• Hematologic Disorders: Pathophysiology and etiology of various anemias,
including Iron deficiency, Vitamin B12 deficiency (pernicious), Aplastic, and Sickle
Cell anemia.
• Endocrinology & Respirology: Understanding the progression of conditions like
COVID-19 pneumonia and the development of complications like Diabetic
Ketoacidosis (DKA).
• Circulatory & Systemic Issues: The four stages of shock (Initial, Compensatory,
Progressive, Refractory) and the manifestations of organ failure.
• Blood Cells: Diagnostic indicators such as decreased hematocrit, pancytopenia, and
characteristic erythrocyte shapes for different diseases.
Quiz_________________?
- A single 'toxic' nodule is comprised of thyroid cells which have lost their regulatory
mechanism that dictates how much hormone to produce
- Without this regulatory control, the cells in this nodule produce thyroid hormone at a
dramatically increased rate causing symptoms of hyperthyroidism
1
, -Some nodules are "cold" since they don't produce any hormone at all -
Answer✅
What is toxic nodular disease?
Quiz_________________?
- Abdominal cramps
- nausea
- vomiting
- lethargy
- weakness -
Answer✅
Signs and Symptoms of Electrolyte Imbalances (K+/NA+)
Quiz_________________?
- Activated during injury
- Form clumps (agglutination) -
Answer✅
What is the platelet response to blood loss?
Quiz_________________?
- affecting large arteries
- abnormal lipid levels -
Answer✅
2
, Diabetes: Macroangiopathy
Quiz_________________?
- Amount of hemoglobin per unit volume of blood
- Mean corpuscular volume (MCV)
- Indicates the oxygen-carrying capacity of blood -
Answer✅
What does hemoglobin measure?
Quiz_________________?
- Anxiety, confusion, dizziness
- Sense of impending doom
- Chest pain
- Incontinence
- Swelling of the lips and tongue, angioedema
- wheezing
- respiratory distress and circulatory failure -
Answer✅
What are clinical manifestations of anaphylaxis?
Quiz_________________?
- arterial line
- central line
- blood work -
3
, Answer✅
What diagnostic tests would you do to confirm cardiogenic shock?
Quiz_________________?
- Blood loss
- Decreased production of erythrocytes
- Increased destruction of erythrocytes -
Answer✅
What is the etiology of anemia?
Quiz_________________?
- Blood test
(Hemoglobin electrophoresis)
- Prenatal DNA analysis -
Answer✅
What are the diagnostic tests used to identify sickle cell anemia?
Quiz_________________?
- bone marrow
- liver
- lympth system -
Answer✅
4