USMLE Step 3 QUESTIONS AND
VERIFIED CORRECT ANSWERS
GRADED A+ LATEST 100%
GUARANTEED PASS
Piperacillin and ticarcillin - CORRECT ANSWER-GNRs
strep
anaerobes
Carbapenems - CORRECT ANSWER-good anaerobic coverage
strep
MSSA
Tigecycline - CORRECT ANSWER-MRSA
good GNR coverage
Anaerobes - CORRECT ANSWER--metronidazole is BEST for abdominal anaerobes
(carbapenems, piperacillin, and ticarcillin have equal efficacy)
-cefoxitin and cefotetan are the ONLY cephalosporins
-respiratory anaerobes: clindamycin
,Abx with NO anaerobic coverage - CORRECT ANSWER-aminoglycs, aztreonam, fluoroquinolones,
oxacillin/nafcillin, all cephalosporins EXCEPT cefoxitin and cefotetan
Red man syndrome - CORRECT ANSWER-red, flushed skin from histamine release, associated
with rapid infusion of vancomycin (so slow down the infusion rate)
Osteomyelitis - CORRECT ANSWER--most common is staph: oxacillin or nafcillin IV for 4-6 wks
for MSSA; vanc, linezolid or dapto for MRSA
-GNRs: salmonella or pseudomonas, can use orals, but must cx org. first and make sure it is
sensitive (BONE bx and cx)
Cellulitis tx - CORRECT ANSWER--minor infection: oral dicloxacillin or cephalexin
-severe: IV oxacillin, nafcillin or cefazolin
-PCN allergy: if rash, then cephalosporin; if anaphylaxis, then vanc, linezolid, dapto (macrolides
or clinda for minor infection)
Sequelae of strep infection - CORRECT ANSWER--throat: rheumatic fever AND
glomerulonephritis
-skin: ONLY glomerulonephritis
Gonorrhea tx - CORRECT ANSWER--ceftriaxone IM
-cefixime oral
-cefpodoxime oral
-ciprofloxacin oral (2d line)
-if pregnant, then ceftriaxone IM
-ALSO treat for chlamydia
,Chlamydia tx - CORRECT ANSWER--azithromycin (single dose)
-doxycycline (for 1 wk)
-if pregnant, then azithro
-ALSO treat for gonorrhea
Recurrent gonorrhea associated with... - CORRECT ANSWER-terminal complement deficiency
(predisposes to any Neisseria infection)
PID tx - CORRECT ANSWER--outpatient: ceftriaxone (IM) and oral doxy
-inpatient: cefoxitin or cefotetan IV + doxy + (maybe) metronidazole
Abx safe in pregnancy - CORRECT ANSWER--PCNs
-cephalosporins
-aztreonam
-erythromycin
-azithromycin
Epidydimo-orchitis tx - CORRECT ANSWER--if <35 yo, then ceftriaxone + doxy
-if >35 yo, then fluoroquinolone
Chancroid - CORRECT ANSWER--PAINFUL ulcer caused by Hemophilus ducreyi
-swab for gram stain and culture (on Nairobi medium or Mueller-Hinton agar)
-treat with ceftriaxone IM or single dose azithromycin
What treats MRSA and VRE? - CORRECT ANSWER-daptomycin
, What binds toxin in gas gangrene? - CORRECT ANSWER-clindamycin
Common bugs in dog bite - CORRECT ANSWER-Capnocytophaga canimorsus (GNR) most
common, Pasteurella multocida may be present in 25%, anaerobes
Bug that causes overwhelming sepsis in asplenics with dog bite - CORRECT ANSWER-
Capnocytophaga canimorsus
Typical bugs in cat bite - CORRECT ANSWER-Pastuerella multocida, anaerobes
Typical bugs in reptile bite - CORRECT ANSWER-Salmonella, Pseudomonas (snakes)
Treatment for animal bite - CORRECT ANSWER-Amox/clavulanate
PCN allergy: doxy OR TMP/SMX OR fluoroquinolone PLUS clinda for anaerobes
Severe infxn: use IV (like unasyn)
Duration: 3-5 days for prophy, 7-14 days for infection
Typical bugs in human bites - CORRECT ANSWER-Eikenella corrodens, streptococci,
staphylococci, Haemophilus species, and a multitude of anaerobes
Treatment for human bite - CORRECT ANSWER-Same as animal bite but be careful tendons or
bones not involved if clenched fist
Common bugs in diabetic foot ulcer - CORRECT ANSWER-staphylococci, streptococci, enteric
gram-negative rods, P. aeruginosa, and anaerobes
Treatment of diabetic foot ulcer - CORRECT ANSWER-Broad until cx results known (if severe
infection): must cover GPC, GNR, and anaerobes, eg vanc + mero
VERIFIED CORRECT ANSWERS
GRADED A+ LATEST 100%
GUARANTEED PASS
Piperacillin and ticarcillin - CORRECT ANSWER-GNRs
strep
anaerobes
Carbapenems - CORRECT ANSWER-good anaerobic coverage
strep
MSSA
Tigecycline - CORRECT ANSWER-MRSA
good GNR coverage
Anaerobes - CORRECT ANSWER--metronidazole is BEST for abdominal anaerobes
(carbapenems, piperacillin, and ticarcillin have equal efficacy)
-cefoxitin and cefotetan are the ONLY cephalosporins
-respiratory anaerobes: clindamycin
,Abx with NO anaerobic coverage - CORRECT ANSWER-aminoglycs, aztreonam, fluoroquinolones,
oxacillin/nafcillin, all cephalosporins EXCEPT cefoxitin and cefotetan
Red man syndrome - CORRECT ANSWER-red, flushed skin from histamine release, associated
with rapid infusion of vancomycin (so slow down the infusion rate)
Osteomyelitis - CORRECT ANSWER--most common is staph: oxacillin or nafcillin IV for 4-6 wks
for MSSA; vanc, linezolid or dapto for MRSA
-GNRs: salmonella or pseudomonas, can use orals, but must cx org. first and make sure it is
sensitive (BONE bx and cx)
Cellulitis tx - CORRECT ANSWER--minor infection: oral dicloxacillin or cephalexin
-severe: IV oxacillin, nafcillin or cefazolin
-PCN allergy: if rash, then cephalosporin; if anaphylaxis, then vanc, linezolid, dapto (macrolides
or clinda for minor infection)
Sequelae of strep infection - CORRECT ANSWER--throat: rheumatic fever AND
glomerulonephritis
-skin: ONLY glomerulonephritis
Gonorrhea tx - CORRECT ANSWER--ceftriaxone IM
-cefixime oral
-cefpodoxime oral
-ciprofloxacin oral (2d line)
-if pregnant, then ceftriaxone IM
-ALSO treat for chlamydia
,Chlamydia tx - CORRECT ANSWER--azithromycin (single dose)
-doxycycline (for 1 wk)
-if pregnant, then azithro
-ALSO treat for gonorrhea
Recurrent gonorrhea associated with... - CORRECT ANSWER-terminal complement deficiency
(predisposes to any Neisseria infection)
PID tx - CORRECT ANSWER--outpatient: ceftriaxone (IM) and oral doxy
-inpatient: cefoxitin or cefotetan IV + doxy + (maybe) metronidazole
Abx safe in pregnancy - CORRECT ANSWER--PCNs
-cephalosporins
-aztreonam
-erythromycin
-azithromycin
Epidydimo-orchitis tx - CORRECT ANSWER--if <35 yo, then ceftriaxone + doxy
-if >35 yo, then fluoroquinolone
Chancroid - CORRECT ANSWER--PAINFUL ulcer caused by Hemophilus ducreyi
-swab for gram stain and culture (on Nairobi medium or Mueller-Hinton agar)
-treat with ceftriaxone IM or single dose azithromycin
What treats MRSA and VRE? - CORRECT ANSWER-daptomycin
, What binds toxin in gas gangrene? - CORRECT ANSWER-clindamycin
Common bugs in dog bite - CORRECT ANSWER-Capnocytophaga canimorsus (GNR) most
common, Pasteurella multocida may be present in 25%, anaerobes
Bug that causes overwhelming sepsis in asplenics with dog bite - CORRECT ANSWER-
Capnocytophaga canimorsus
Typical bugs in cat bite - CORRECT ANSWER-Pastuerella multocida, anaerobes
Typical bugs in reptile bite - CORRECT ANSWER-Salmonella, Pseudomonas (snakes)
Treatment for animal bite - CORRECT ANSWER-Amox/clavulanate
PCN allergy: doxy OR TMP/SMX OR fluoroquinolone PLUS clinda for anaerobes
Severe infxn: use IV (like unasyn)
Duration: 3-5 days for prophy, 7-14 days for infection
Typical bugs in human bites - CORRECT ANSWER-Eikenella corrodens, streptococci,
staphylococci, Haemophilus species, and a multitude of anaerobes
Treatment for human bite - CORRECT ANSWER-Same as animal bite but be careful tendons or
bones not involved if clenched fist
Common bugs in diabetic foot ulcer - CORRECT ANSWER-staphylococci, streptococci, enteric
gram-negative rods, P. aeruginosa, and anaerobes
Treatment of diabetic foot ulcer - CORRECT ANSWER-Broad until cx results known (if severe
infection): must cover GPC, GNR, and anaerobes, eg vanc + mero
