NBME CBSE (Comprehensive Basic Science Examination) EXAM
Exam Coverage
Exam coverage for the NBME CBSE (Comprehensive Basic Science
Examination) includes foundational medical sciences used to assess
readiness for exams like USMLE Step 1, administered by the National
Board of Medical Examiners (NBME). It focuses on disciplines such as
anatomy, physiology, biochemistry, microbiology, pathology,
pharmacology, and behavioral sciences. The exam also evaluates
understanding of disease mechanisms, basic clinical correlations, and
application of scientific principles to medical scenarios.
,Polio live v killed vaccine
Killed = Salk = IgG
Live = Sabin = IgG + IgA
- can be shed in feces
Neonatal Respiratory Distress:
Etiology + Tx
Maternal DM (high insulin)
or C-section (low cortisol)
TX: dexamethasone before birth
,Lung maturity determined with
Amniocentesis of Phospholipids (*type II pneumocytes)
L >> S
Type II pneumocytes
surfactant (lecithin)
Proliferate after injury
Type I progenitors
Neonatal Respiratory Distress Syndrome
, Type I pneumocytes
Squamous gas diffusion
Elastase in lungs
macrophage: lysosomes
PMN: azuronphilic granules
Elastin stretches and recoils due to
Lysine interchain crosslinks
Exam Coverage
Exam coverage for the NBME CBSE (Comprehensive Basic Science
Examination) includes foundational medical sciences used to assess
readiness for exams like USMLE Step 1, administered by the National
Board of Medical Examiners (NBME). It focuses on disciplines such as
anatomy, physiology, biochemistry, microbiology, pathology,
pharmacology, and behavioral sciences. The exam also evaluates
understanding of disease mechanisms, basic clinical correlations, and
application of scientific principles to medical scenarios.
,Polio live v killed vaccine
Killed = Salk = IgG
Live = Sabin = IgG + IgA
- can be shed in feces
Neonatal Respiratory Distress:
Etiology + Tx
Maternal DM (high insulin)
or C-section (low cortisol)
TX: dexamethasone before birth
,Lung maturity determined with
Amniocentesis of Phospholipids (*type II pneumocytes)
L >> S
Type II pneumocytes
surfactant (lecithin)
Proliferate after injury
Type I progenitors
Neonatal Respiratory Distress Syndrome
, Type I pneumocytes
Squamous gas diffusion
Elastase in lungs
macrophage: lysosomes
PMN: azuronphilic granules
Elastin stretches and recoils due to
Lysine interchain crosslinks
