NR 507 Week 8 Exam Final Advanced Pathophysiology Real Exam Questions and
Answers Proctored via Examplify Complete 100 Questions Guaranteed Pass and A+
Score
Which condition results from an autoimmune destruction of acetylcholine receptors at the
neuromuscular junction?
A. Lambert-Eaton syndrome
B. Myasthenia gravis
C. Guillain-Barré syndrome
D. Amyotrophic lateral sclerosis
Correct Answer: B
Rationale: Myasthenia gravis is caused by autoantibodies targeting postsynaptic acetylcholine
receptors, leading to muscle weakness.
,2.
A patient with chronic kidney disease develops metabolic acidosis. Which compensatory mechanism
is expected?
A. Hypoventilation
B. Increased bicarbonate excretion
C. Increased respiratory rate
D. Decreased hydrogen ion secretion
Correct Answer: C
Rationale: The respiratory system compensates for metabolic acidosis by increasing
ventilation to eliminate carbon dioxide.
,3.
Which hormone primarily regulates sodium reabsorption in the distal nephron?
A. Antidiuretic hormone
B. Aldosterone
C. Atrial natriuretic peptide
D. Renin
Correct Answer: B
Rationale: Aldosterone increases sodium reabsorption and potassium secretion in the distal
tubules and collecting ducts.
, 4.
Insulin resistance in type 2 diabetes mellitus is most strongly associated with:
A. Autoimmune beta-cell destruction
B. Increased insulin receptor sensitivity
C. Decreased glucose uptake by peripheral tissues
D. Complete absence of insulin secretion
Correct Answer: C
Rationale: Insulin resistance impairs glucose uptake in skeletal muscle and adipose tissue
despite adequate or elevated insulin levels.
Answers Proctored via Examplify Complete 100 Questions Guaranteed Pass and A+
Score
Which condition results from an autoimmune destruction of acetylcholine receptors at the
neuromuscular junction?
A. Lambert-Eaton syndrome
B. Myasthenia gravis
C. Guillain-Barré syndrome
D. Amyotrophic lateral sclerosis
Correct Answer: B
Rationale: Myasthenia gravis is caused by autoantibodies targeting postsynaptic acetylcholine
receptors, leading to muscle weakness.
,2.
A patient with chronic kidney disease develops metabolic acidosis. Which compensatory mechanism
is expected?
A. Hypoventilation
B. Increased bicarbonate excretion
C. Increased respiratory rate
D. Decreased hydrogen ion secretion
Correct Answer: C
Rationale: The respiratory system compensates for metabolic acidosis by increasing
ventilation to eliminate carbon dioxide.
,3.
Which hormone primarily regulates sodium reabsorption in the distal nephron?
A. Antidiuretic hormone
B. Aldosterone
C. Atrial natriuretic peptide
D. Renin
Correct Answer: B
Rationale: Aldosterone increases sodium reabsorption and potassium secretion in the distal
tubules and collecting ducts.
, 4.
Insulin resistance in type 2 diabetes mellitus is most strongly associated with:
A. Autoimmune beta-cell destruction
B. Increased insulin receptor sensitivity
C. Decreased glucose uptake by peripheral tissues
D. Complete absence of insulin secretion
Correct Answer: C
Rationale: Insulin resistance impairs glucose uptake in skeletal muscle and adipose tissue
despite adequate or elevated insulin levels.
