COMPREHENSIVE STUDY GUIDE 2026
FULL QUESTIONS AND SOLUTIONS
GRADED A+
◍ Normal INR range.
Answer: >1.1 in healthy people2-3 if taking Warfarin
◍ What is the most common comorbidity of fatigue?.
Answer: Depression
◍ What are the qualifications for fever of unknown origin?.
Answer: If a fever of >101.3 F occurs at least 3x in a 3-week period in an
ambulatory pt w/ no known cause.If in the hospital, the fever must persist at
least 1 week w/o diagnosis.
◍ What is anterior lymphadenopathy most commonly associated with?.
Answer: Streptococcus pharyngitis
◍ How many months may be spent in the remodeling phase of wound
healing?.
Answer: The remodeling phase can continue for up to 6 months
◍ How many years since the last tetanus booster qualifies you for another one
if you have a wound?.
Answer: If 5 years have elapsed since last booster
◍ Wound cleaning solution recommendation for loosening bebris and
superficial foreign bodies:.
Answer: Shur-Clens solution
◍ What is the prophylactic abx of choice for a wound on someone who has
, DM?.
Answer: Parenteral:-ampicillin/sulbactam-ceftriaxoneOral:-augmentin-cephalexin-ce
◍ Who has the highest incidence of bacterial infections in wounds, what type
of wound?.
Answer: -Crush injuries-Dirty wounds-Jagged wounds-Wounds with
devitalized tissues-Wounds >12-19 hrs old-Bites (w/ feces or
saliva)-Wounds w/ foreign bodies-Wounds w/ subQ stitches
◍ The FNP is seeing a patient with COP
D. The patient had been doing well on salmeterol (Serevent) one puff every
12 hours and tiotropium (Spiriva) two puffs daily. But he is now having an
exacerbation. His eosinophil count is high at 200. According to GOLD
guidelines, what would be the most appropriate next medication to add at
this point?
A. Fluticasone (Flovent) 2 puffs twice daily
B. Prednisone 40 mg daily for 10 days
C. Formoterol (Foradil) 20 mcg nebulizer q 12 hours
D. Roflumilast (Daliresp) 500 mcg daily.
Answer: A. Fluticasone (Flovent) 2 puffs twice dailyThe patient is already
on a LABA and a LAMA. He is having an exacerbation with a high
eosinophil count. Adding an ICS such as Flovent would be most appropriate
(even though EOS is not <300, it is still high and follow-up GOLD states
<100 EOS indicates ICS)A course of oral corticosteroids should be
considered with moderate/severe exacerbations, but the EOS dictates adding
ICS and severity is not specified
◍ A patient with limited-stage small cell lung cancer (SCLC) has undergone
chemotherapy with a good initial response to therapy. What will the
provider tell this patient about the prognosis for treating this disease?
A. There is an 80% chance of 5-year survival
B. Surgical resection will improve survival chances dramatically
C. That relapse is likely with a 2-year overall survival of 50%
D. Treatment will proceed with curative intent.
, Answer: C. That relapse is likely with a 2-year overall survival of
50%SCLC often responds well initially, but the majority of patients relapse
and 2-yr survival is 50%. Treatment is generally palliative
◍ What is the most common cause of burn wounds?.
Answer: Thermal injury
◍ What is the most common form of GI decontamination?.
Answer: Activated charcoal
◍ Heat-related Illness: Management.
Answer: Mild:Calamine lotion & topical steroids for heat
rashModerate-Severe:Remove clothingSpray lukewarm waterIce packs to
groin/axillaFansIV fluidsGoal- Reduce temp to 102 F within the first hour
◍ Which of the following is NOT recommended for the management of
HIV-exposed infants in the
U. S?
A. Routine viral load
B. Breastfeeding
C. Referral to a pediatric HIV specialist
D. Management with HIV antiviral medications.
Answer: B. Breastfeeding
◍ A 3-week-old infant is brought to the ED with a fever of 38.4 C (101.1 F)
for the past 4 hours. The baby is feeding well and has no other symptoms.
On examination, the infant appears well and has normal vital signs except
for the fever. What is the most appropriate next step in management?
A. Perform a full sepsis workup and admit for empiric IV antibiotics
B. Obtain a chest x-ray and start oral antibiotics pending results
C. Obtain a rapid viral panel and start antivirals in the ED
D. Administer antipyretics and discharge with close outpatient follow-up.
Answer: A. Perform a full sepsis workup and admit for empiric IV
antibioticsAny neonates <22 days of age with fever should be hospitalized
and receive a full septic workup (they are septic until proven otherwise)
, ◍ The FNP is seeing a 4 y/o child who has a positive polysomnography
indicating obstructive sleep apnea (OSA). The NP determines which of the
following is the best next step in managing this child's condition?
A. Prescribe intranasal steroids
B. Refer to pediatric neurologist
C. Referral to pulmonology for CPAP management
D. Referral to ENT for evaluation for tonsillectomy and adenoidectomy
surgery.
Answer: D. Referral to ENT for evaluation for tonsillectomy and
adenoidectomy surgeryT & A is considered first-line tx for OSA in children.
CPAP is not first-line but can be considered if T & A is not effective
◍ Hypothermia: Management.
Answer: Remove wet clothing & replace with warm blanketsWarm IV
fluids02Repeat vitals, ABGs, ECGs
◍ In a patient experiencing an acute gout attack, which of the following
diagnostic labs would you expect to be elevated?
A. ESR and creatinine
B. Urine sodium and serum glucose
C. BUN and serum calcium
D. Serum calcium and serum sodium.
Answer: A. ESR and creatinineGout= elevated ESR/CRP, creatinine, and
serum uric acid level
◍ What causes glycogen stores to deplete in a hypothermic pt?.
Answer: Shivering
◍ The FNP has been seeing a patient who has bone pain. Lab studies reveal an
elevated serum alkaline phosphatase (ALP). The NP suspects Paget's
Disease. Which initial test can help distinguish Paget's from a bone tumor?
A. Bone radiograph/x-ray
B. Bone scan
C. Bone densitometry
D. Bone marrow biopsy.