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naltrexone class - (Answer)Opioid receptor antagonist
Naltrexone can be used for - (Answer)both ETOH and opioid use disorders
What does naltrexone do - (Answer)Reduces desire/cravings, First line treatment, Will
precipitate withdrawal in patients with physical opioid dependence
First line treatment in maintaining abstinence after detox - (Answer)acamprosate
acamprosate can be used - (Answer)in liver disease- not metabolized by the liver (not impacted
by ETOH use). Can be administered to patients with hepatitis, liver disease, and those who
continue drinking alcohol
acamprosate Contraindicated in - (Answer)severe renal disease
acamprosate helps with - (Answer)Decreasing cravings
,ETOH 2nd line treatment - (Answer)disulfiram (Antabuse)
disulfiram (Antabuse) causes - (Answer)aversion reaction to ETOH (flushing, headaches, n/v,
palpitation, SOB, vertigo, hypotension)
disulfiram (Antabuse) Do not - (Answer)administer until the person has been alcohol free at least
12 hours
disulfiram (Antabuse) MOA - (Answer)Blocks enzyme (aldehyde dehydrogenase) in the liver
ETOH withdrawal- Benzos - (Answer)To keep patient calm and lightly sedated
Benzos MOA - (Answer)Enhance the effects of GABA
Meds used in mild alcohol withdrawal - (Answer)Tegretol, Valproic or Gabapentin
ETHO meds for nutritional deficiencies - (Answer)Thiamine, folic acid, and multivitamin -
'Banana bag'
, Wernicke's encephalopathy treatment - (Answer)Parenteral Thiamine and Folate
Wernicke's encephalopathy cause - (Answer)B1 deficiency
Cocaine mechanism - (Answer)reuptake of dopamine, epinephrine, and NE = Stimulant effect
Cocaine effects on the body - (Answer)has vasoconstrictive effects = can cause MI, stroke
Cocaine treatment options - (Answer)NO FDA approved med; Off-label = naltrexone, modafinil,
Topamax
Antabuse in cocaine use disorder - (Answer)increase synaptic dopamine in the brain reward
circuit and act as an agonist treatment in the setting of cocaine use disorder
Medications for cocaine-induced chest pain - (Answer)nitroglycerin & aspirin = No metoprolol
Amphetamine treatment - (Answer)Rehydrate, correct electrolyte, and treat hyperthermia
PCP symptoms of intoxication - (Answer)Nystagmus