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What is the mechanism of action of Naloxone? - (Answer)Pure opioid antagonist that competes
and displaces opioids receptor sites.
What medications treat opioid disorder? - (Answer)Methadone;
Buprenorphine, buprenorphine + Naloxone
What medication for opioid use disorder is used with comorbid pain? - (Answer)Buprenorphine
+ Naloxone
Inappropriate use of what substance may be due to uncontrolled pain? - (Answer)Opioids
What are the Naltrexone delivery methods? - (Answer)Tablet;
Injectable;
Implant
What is one form of Naltrexone delivery method limited to inpatient use? - (Answer)Implant
,What is the mechanism of action buprenorphine? - (Answer)Mu receptor partial agonist for
opioid withdrawal
What medication taken too soon after last opioid use increases the chances of intense withdrawal
that comes on very quickly (precipitated withdrawal)? - (Answer)Buprenorphine
What are symptoms of opioid intoxication? - (Answer)Nausea and vomiting;
Respiratory depression;
Constipation;
Itching;
Mioisis (small pupil);
Euphoria; and
Sedation
What withdrawal symptoms of opioids? - (Answer)Nausea and vomiting;
Diarrhea;
Dehydration;
Irritability;
Restlessness;
, Yawning;
Twitching;
Increased heart rate and blood pressure;
Chills;
Increased temperature;
Rhinorrhea;
Lacrimation;
Dilated pupils
What medication is given for opioid intoxication during cardiac or respiratory depression is a
concern? - (Answer)Naloxone
What are symptoms of cocaine intoxication? - (Answer)Dilated pupils;
Headache;
Tremor;
Hyper-reflexia;
Twitching;
MI;
Nausea and vomiting;