NAPSRx CNPR Exam (Revised 18th Edition) Exam
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(2026) UPDATE |2026!! STUDY GUIDE EXAM
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Terms in this set (649)
what does a STAT order mean? a drug needed immediately and given only once
what information does the signs, symptoms and treatment of acute overdoses
overdosage section of the labeling
provide?
types of drug-drug interactions: duplication, opposition (antagonism) and alteration
(p.51)
tolerance vs resistance tolerance is the diminished response to a drug;
resistance is the cells ability to resist the effects of
the drug on them.
abbreviated new drug application the process by which applicants must scientifically
(ANDA) demonstrate to the FDA that their generic product
is bioequivalent to or performs in the same way as
the innovator drug, no duplicate testing (p. 75)
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the Hatch-Waxman Act of 1984 -A.K.A. Drug Price Competition and Patent
Restoration Act
-made it easier to bring generic drugs to the
market by requiring the FDA to only look at
bioavailability studies in order to approve an
ANDA.
-gave protection to the research based
manufacturers by providing a 30-month automatic
cooling off period once an ANDA is challenged for
patent infringement (p. 75)
four basic transport mechanisms passive diffusion, facilitated diffusion, active
transport, and pinocytosis (p. 95)
potency vs efficacy potency: amount of drug necessary to produce
desired effect
efficacy: magnitude of maximal response that can
be received from a drug
efficacy is almost always more important that
potency (p. 106)
the four phases of clinical trials phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias sampling error is unbiased and is randomly chosen
from the population.
selection bias is when the sample was specifically
chosen based on particular characteristics (p.142-
143)
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independent vs dependent variable An independent variable is the one that influences
the variation. A dependent variable is the variable
being tested and measured in a scientific
experiment (the result of applying the independent
variable).
Drug Utilization Review (DUR) -involve retrospective monitoring of physicians'
programs prescribing patterns
-more than 90% of HMOs require DURs
-nowadays mostly monitors cost savings (p. 181)
opportunity cost based on the premise that all resources are scarce,
and therefore every time we choose to use a
resource it reduces the possibility of it being used
in another way.
what type of DTC advertising is the Disease-state or unbranded ads (provides public
only legal form in Europe? information on a disease, not a drug)
(p. 223)
can pharm sales reps offer doctors company reps can only offer occasional meals as
meals? (PhRMA code) long as they are modest, and only offered in an
office/hospital setting in conjunction with an
educational presentation. (p. 228)
FAQ about the PhRMA code p. 268-274
Urology and selling to Urologists p. 300-301
what is a Medical Science Liaison they serve as educators and field-based medical
(MLS)? resources. they interface between their company
and healthcare leaders.
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push through vs pull through sales - push-through refers to the company's overall
strategies efforts to demonstrate clinical efficiency and
efficacy and cost effectiveness of a product.
- pull-through generates demand for the product,
usually in ways consistent with the health plans
goals and guidelines. (p. 311)
drug labeling requirements FDA https://www.fda.gov/about-fda/oncology-center-
excellence/how-do-i-use-prescription-drug-
labeling#Section-10
What is predictive validity? the ability of an indicator to correctly predict an
outcome.
what are some of the criteria that *the size of the target patient population
influence the decision to use mass the chronicity of the disease state
advertising in pharmaceutical the relevance of that disease state to its sufferers
marketing? the avg value of a patient taking medication
according to the AMA guidelines, conference sponsors
who should accept subsidies for
continuing medical education
conferences?
who is the decision maker in the physician
pharmaceutical sales?
"fast track drugs" refer to drugs approved for serious or life-threatening
conditions
rebate definition the amount that the manufacturer of a drug pays to
an insurer or health plan for each unit of drug
dispensed.
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