ADVANCED PATHOPHYSIOLOGY UTMB 5355
EXAM 2026 DISEASE PROGRESSION DRILL
PACK ANSWER SHEET
◉ Which of the following is a role of histamine when released by
mast cells?
Answer: Increased Vascular Permeability
◉ Which of the following results when histamine attaches to the H1
receptor?
Answer: Smooth muscle contraction, increased chemotaxis,
stimulation of prostaglandin synthesis
◉ Which chemical mediator is responsible for prolonged asthma
symptoms such as bronchoconstriction and inflammation?
Answer: Leukotrienes
◉ Which of the following are an active modulator of allergic
reactions in the immune system?
Answer: Eosinophils
,◉ directs movement of cells along a chemical gradient attracting
eosinophils and neutrophils to the site of inflammation.
Answer: Chemotaxis
◉ What are the functions of interferons?
Answer: Protect against viral infection, modulate inflammatory
response
◉ Your patient has seasonal allergic rhinitis. Which type of
hypersensitivity reaction is this?
Answer: Type 1
◉ Your patient has diagnosis of Grave's disease. Which type of
Hypersensitivity reaction is this?
Answer: Type 2
◉ Which of the following is a type III hypersensitivity reaction?
Answer: Glomerulonephritis
◉ Which of the following statement is true regarding Type IV
Reactions?
Answer: The reaction is mediated by T lymphocytes
, ◉ Which of the following statements are true regarding exotoxins?
Answer: damage cell membranes, activate second messengers,
inhibit protein synthesis
◉ immunity is produced by an individual after natural exposure to
an antigen or after immunization
Answer: Active
◉ immunity produces immunoglobulins that bind to antigens and
neutralize their effects
Answer: Humoral
◉ stimulates the proliferation of T cells and B cells during
inflammation
Answer: Interleukins
◉ Catecholamines decrease which of the following immune system
cells during chronic stress?
Answer: Natural Killer cells
◉ interfere with insulin signaling leading to insulin resistance in
stress, obesity, and Type 2 Diabetes.
Answer: Pro-inflammatory cytokines
EXAM 2026 DISEASE PROGRESSION DRILL
PACK ANSWER SHEET
◉ Which of the following is a role of histamine when released by
mast cells?
Answer: Increased Vascular Permeability
◉ Which of the following results when histamine attaches to the H1
receptor?
Answer: Smooth muscle contraction, increased chemotaxis,
stimulation of prostaglandin synthesis
◉ Which chemical mediator is responsible for prolonged asthma
symptoms such as bronchoconstriction and inflammation?
Answer: Leukotrienes
◉ Which of the following are an active modulator of allergic
reactions in the immune system?
Answer: Eosinophils
,◉ directs movement of cells along a chemical gradient attracting
eosinophils and neutrophils to the site of inflammation.
Answer: Chemotaxis
◉ What are the functions of interferons?
Answer: Protect against viral infection, modulate inflammatory
response
◉ Your patient has seasonal allergic rhinitis. Which type of
hypersensitivity reaction is this?
Answer: Type 1
◉ Your patient has diagnosis of Grave's disease. Which type of
Hypersensitivity reaction is this?
Answer: Type 2
◉ Which of the following is a type III hypersensitivity reaction?
Answer: Glomerulonephritis
◉ Which of the following statement is true regarding Type IV
Reactions?
Answer: The reaction is mediated by T lymphocytes
, ◉ Which of the following statements are true regarding exotoxins?
Answer: damage cell membranes, activate second messengers,
inhibit protein synthesis
◉ immunity is produced by an individual after natural exposure to
an antigen or after immunization
Answer: Active
◉ immunity produces immunoglobulins that bind to antigens and
neutralize their effects
Answer: Humoral
◉ stimulates the proliferation of T cells and B cells during
inflammation
Answer: Interleukins
◉ Catecholamines decrease which of the following immune system
cells during chronic stress?
Answer: Natural Killer cells
◉ interfere with insulin signaling leading to insulin resistance in
stress, obesity, and Type 2 Diabetes.
Answer: Pro-inflammatory cytokines
