ADVANCED PHARMACOLOGY FOR
PRESCRIBERS CERTIFICATION EVALUATION
2026 EXAM SCRIPT FULLY SOLVED
QUESTIONS
◉Doxycycline - type of drug. Answer: Tetracycline
◉Doxycycline - MOA. Answer: bacteriostatic, inhibits protein
synthesis
Anti-inflammatory properties
Preg Cat D
◉Doxycycline - Indication. Answer: Treat infections caused by:
Mycoplasma, Chlamydia, Rickettsia, Borrelia burgdorferi.
-genital C. trachomatis infection (1st line)
-Lyme disease (1st line)
-anthrax inhalation post exposure and cutaneous anthrax.
-syphilis in patients allergic to penicillin.
-Acute exacerbations of chronic bronchitis.
,-Treat acne rosacea/vulgaris
-H. pylori
-MRSA
Caution: renal impairment, hepatic impairment
CI: children <8 yrs (bone/teeth abnormality), pregnancy
(hepatotoxicity)
◉Doxycycline - Monitor. Answer: Assess periodically for rash.
Discontinue use if rash accompanied with fever, fatigue, joint aches,
blisters, oral lesions, hepatitis
Long term management: liver function
◉Doxycycline - ADR. Answer: Sun sensitivity
GI disturbance
Blood dyscrasias
Steven Johnson Syndrome, toxic epidermal necrolysis.
intracranial hypertension aka benign intracranial hypertension
Increase warfarins anticoag effects.
Can interfere w/ estrogen-containing oral contraceptive. Backup
recommended.
,*Must not take with any iron or calcium containing products
(separate by 2 hours)
◉Rifampin - type of drug. Answer: antimycobacterials
◉Rifampin - MOA. Answer: Inhibits RNA synthesis
Bactericidal
Preg Cat A
◉Rifampin - Indication. Answer: 1st line for Tuberculosis (as part of
combined drug therapy)
meningococcal meningitis prophylaxis
H. influenzae meningitis prophylaxis (off-label)
Staphylococcal infections as part of combination therapy
◉Rifampin - Monitor. Answer: Careful monitoring for hepatotoxicity:
hepatic function (ALT/AST) prior to and at least monthly during
treatment
Educate to report signs of hepatitis (dark urine, yellow eyes or skin)
, Monitor CBC if signs of blood dyscrasia (sore throat, bleeding,
bruising)
Pregnancy: use is recommended because risk of losing the fetus
secondary to tuberculosis infection or because of congenital
tuberculosis poses a higher risk than the observed risks of adverse
effects of treatment
◉Rifampin ADRs. Answer: -harmless red/orange urine, sweat, tears,
saliva and onto contact lens,
-Rashes, thrombocytopenia, nephritis, impaired liver function, flu-
like symptoms
◉Acyclovir (Zovirax) - type of drug. Answer: Antiviral; Nucleoside
Analog
◉Acyclovir - MOA. Answer: Inhibits viral DNA synthesis
Preg cat B
◉Acyclovir - Indication. Answer: -Genital Herpes (initial,
intermittent, chronic therapy)
-Herpes Zoster (shingles)
-Gingivostomatitis in children
PRESCRIBERS CERTIFICATION EVALUATION
2026 EXAM SCRIPT FULLY SOLVED
QUESTIONS
◉Doxycycline - type of drug. Answer: Tetracycline
◉Doxycycline - MOA. Answer: bacteriostatic, inhibits protein
synthesis
Anti-inflammatory properties
Preg Cat D
◉Doxycycline - Indication. Answer: Treat infections caused by:
Mycoplasma, Chlamydia, Rickettsia, Borrelia burgdorferi.
-genital C. trachomatis infection (1st line)
-Lyme disease (1st line)
-anthrax inhalation post exposure and cutaneous anthrax.
-syphilis in patients allergic to penicillin.
-Acute exacerbations of chronic bronchitis.
,-Treat acne rosacea/vulgaris
-H. pylori
-MRSA
Caution: renal impairment, hepatic impairment
CI: children <8 yrs (bone/teeth abnormality), pregnancy
(hepatotoxicity)
◉Doxycycline - Monitor. Answer: Assess periodically for rash.
Discontinue use if rash accompanied with fever, fatigue, joint aches,
blisters, oral lesions, hepatitis
Long term management: liver function
◉Doxycycline - ADR. Answer: Sun sensitivity
GI disturbance
Blood dyscrasias
Steven Johnson Syndrome, toxic epidermal necrolysis.
intracranial hypertension aka benign intracranial hypertension
Increase warfarins anticoag effects.
Can interfere w/ estrogen-containing oral contraceptive. Backup
recommended.
,*Must not take with any iron or calcium containing products
(separate by 2 hours)
◉Rifampin - type of drug. Answer: antimycobacterials
◉Rifampin - MOA. Answer: Inhibits RNA synthesis
Bactericidal
Preg Cat A
◉Rifampin - Indication. Answer: 1st line for Tuberculosis (as part of
combined drug therapy)
meningococcal meningitis prophylaxis
H. influenzae meningitis prophylaxis (off-label)
Staphylococcal infections as part of combination therapy
◉Rifampin - Monitor. Answer: Careful monitoring for hepatotoxicity:
hepatic function (ALT/AST) prior to and at least monthly during
treatment
Educate to report signs of hepatitis (dark urine, yellow eyes or skin)
, Monitor CBC if signs of blood dyscrasia (sore throat, bleeding,
bruising)
Pregnancy: use is recommended because risk of losing the fetus
secondary to tuberculosis infection or because of congenital
tuberculosis poses a higher risk than the observed risks of adverse
effects of treatment
◉Rifampin ADRs. Answer: -harmless red/orange urine, sweat, tears,
saliva and onto contact lens,
-Rashes, thrombocytopenia, nephritis, impaired liver function, flu-
like symptoms
◉Acyclovir (Zovirax) - type of drug. Answer: Antiviral; Nucleoside
Analog
◉Acyclovir - MOA. Answer: Inhibits viral DNA synthesis
Preg cat B
◉Acyclovir - Indication. Answer: -Genital Herpes (initial,
intermittent, chronic therapy)
-Herpes Zoster (shingles)
-Gingivostomatitis in children
