Epinephrine receptors - ANSWERalpha 1, alpha 2, beta 1, beta 2
Epinephrine dose - ANSWERIV 2-10mcg/min
Epinephrine effects - ANSWERincreased systolic BP
- alpha receptors = vasoconstriction
- beta1 receptor = cardiac stimulant
decreased diastolic BP
- beta2 = dilation of skeletal muscle blood vessel
Phenylephrine receptors - ANSWERalpha 1
Phenylephrine dose - ANSWER40-200 mcg/min
Phenylephrine effects - ANSWERvasoconstriction, and reflex bradycardia
Milrinone mechanism of action - ANSWERInhibits PDE-3 → ↑cAMP
↑ cAMP in heart: ↑[Ca]cytosol → inotropic
↑ cAMP in blood vessels: ↑Ca reuptake by sarcoplasmic reticulum → vasodilation
Epinephrine mechanism of action - ANSWERDirect-acting alpha and beta agonist. Alpha:
vasoconstriction. Beta-1: positive inotropic, chronotropic, and dromotropic effects. Beta-2: bronchial
smooth muscle relaxation and dilation of skeletal vasculature. Blocks histamine receptors.
milrinone - ANSWERphosphodiesterase inhibitor
Epinephrine dose - ANSWERIV 2-10mcg/min
Epinephrine effects - ANSWERincreased systolic BP
- alpha receptors = vasoconstriction
- beta1 receptor = cardiac stimulant
decreased diastolic BP
- beta2 = dilation of skeletal muscle blood vessel
Phenylephrine receptors - ANSWERalpha 1
Phenylephrine dose - ANSWER40-200 mcg/min
Phenylephrine effects - ANSWERvasoconstriction, and reflex bradycardia
Milrinone mechanism of action - ANSWERInhibits PDE-3 → ↑cAMP
↑ cAMP in heart: ↑[Ca]cytosol → inotropic
↑ cAMP in blood vessels: ↑Ca reuptake by sarcoplasmic reticulum → vasodilation
Epinephrine mechanism of action - ANSWERDirect-acting alpha and beta agonist. Alpha:
vasoconstriction. Beta-1: positive inotropic, chronotropic, and dromotropic effects. Beta-2: bronchial
smooth muscle relaxation and dilation of skeletal vasculature. Blocks histamine receptors.
milrinone - ANSWERphosphodiesterase inhibitor
