RUTGERS MURPHY BIOCHEM EXAM 3
QUESTIONS AND ANSWERS
1. In nucleosome structure the
histone aids in stabilizing the wrapping
of DNA around the protein octomer.
Answer H1
2. The DNA "backbone" is composed of
Answer A phosphodiester bond between 3' and 5' hydroxyl groups
of adjacent deoxyribose residues
3. Which of the following statements is not true of mRNA?
Answer Prokaryotic mRNAs are capped with 7-methylguanosine
4. Point mutations that occur in a population to any extent are
referred to as
Answer Single nucleotide polymorphisms
1/
6
, 5. Determine the mRNA sequence for the following DNA sequence.5'-
GCCAT- TTCCCGTTA-3'
Answer 5'-UAACGGGAAAUGGC-3'
6. The experiment that demonstrated the mechanism whereby DNA is
synthe- sized was performed by
Answer Messelson and Stahl
7. Which of the following is not a second messenger molecule?
Answer Steroids
8. Nucleosome
s are composed of all of the following except .
Answer H5
9. The classic experiment that demonstrated that radioactively labeled
viral DNA transforms bacterial cells was performed by
Answer Hershey and Chase
10. A scientist performs an experiment that uses a chemical inhibitor
2/
6
QUESTIONS AND ANSWERS
1. In nucleosome structure the
histone aids in stabilizing the wrapping
of DNA around the protein octomer.
Answer H1
2. The DNA "backbone" is composed of
Answer A phosphodiester bond between 3' and 5' hydroxyl groups
of adjacent deoxyribose residues
3. Which of the following statements is not true of mRNA?
Answer Prokaryotic mRNAs are capped with 7-methylguanosine
4. Point mutations that occur in a population to any extent are
referred to as
Answer Single nucleotide polymorphisms
1/
6
, 5. Determine the mRNA sequence for the following DNA sequence.5'-
GCCAT- TTCCCGTTA-3'
Answer 5'-UAACGGGAAAUGGC-3'
6. The experiment that demonstrated the mechanism whereby DNA is
synthe- sized was performed by
Answer Messelson and Stahl
7. Which of the following is not a second messenger molecule?
Answer Steroids
8. Nucleosome
s are composed of all of the following except .
Answer H5
9. The classic experiment that demonstrated that radioactively labeled
viral DNA transforms bacterial cells was performed by
Answer Hershey and Chase
10. A scientist performs an experiment that uses a chemical inhibitor
2/
6
