HEMA MOCK BOARDS EXAM WITH
100% CORRECT ANSWERS
2026/2027
In the bone marrow, erythroid precursors are located:
A Surrounding macrophages in erythroid islands
B Adjacent to megakaryocytes along the adventitial cell lining
C Surrounding fat cells in apoptotic islands
D In the center of the hematopoietic cords CORRECT ANSWER: A Surrounding
macrophages in erythroid islands
Which of the following are characteristics of pluripotential hematopoietic stem
cells? I. Possess self-renewal ability II. Produces progenitor cells committed to a
particular cell lineage III. Morphologically unrecognizable IV. Expression of CD34
V. Expression of CD38
A. IandII
B. IandIV
C. I, II, III, and IV
D. I, II, III, IV, and V CORRECT ANSWER: D. I, II, III, IV, and V
Which of the following statements characterize erythropoietin (EPO) function? I.
Transforms the CFU-E into the earliest recognizable RBC precursor II. Increases
the rate of red blood cell production by the bone marrow III. Shortens the
maturation time of developing erythroid precursors IV. Decreases stimulation of
erythropoiesis when cellular hypoxia increases
A. I and II
B. I, II, and III
,C. II and III
D. I, II, III, and IV CORRECT ANSWER: B. I, II, and III
All of these are correct, except:
A. The kidneys recognize the tissue hypoxia through the peritubular cells of the
interstitium.
B. Tissue hypoxia is a prime stimulant for erythropoietin production.
C. Apoptosis is a physiologic process and its inhibition may also occur.
D. Erythropoietin acts mainly on pronormoblast. CORRECT ANSWER: D.
Erythropoietin acts mainly on pronormoblast.
Which of the following factors will result in an increase in oxygen delivery to the
tissues?
I. Increased blood pH II. High altitudes III. Increased hemoglobin binding of 2,3-
BPG
IV. Increased compensatory Hemoglobin F V. Increased carbon
dioxide
A. I, II, III, and IV
B. II and III
C. II, III, and V
D. I, II, III, and V CORRECT ANSWER: C. II, III,
and V
True for Sulfhemoglobinemia. Select all that apply. I. Reversible oxidation of
hemoglobin II. reported upon exposure to sulfur drugs e.g. sulfanilamide III.
Reported in patients with severe constipation in cases of severe bacteremia due
to Clostridium perfringens IV. Can be measured using Cyanmethemoglobin
method V. gives blood a mauve lavender discoloration
A. II and V
B. II and III
C. I, II, and III
D. II, III, and V CORRECT ANSWER: D. II, III,
and V
The EMP net gain of 2 ATP provides high energy phosphates to all of the
following
EXCEPT:
A. Maintenance of membrane
lipids
B. Power that cation pump needed for Na-K concentration pump and Ca
flux
, C. Preserve the shape and flexibility of the cellular
membrane
D. Gas exchange between the lungs and blood CORRECT ANSWER: D. Gas
exchange
between the lungs and
blood
What is the percent transferrin saturation for a patient with total serum iron of 63
mg/dL and TIBC of 420 mg/dL?
A. 0.15%
B. 1.2%
C. 12%
D. 15%
E. 80% CORRECT ANSWER: D. 15%
A 56-year-old man was admitted to the hospital for treatment of a bleeding ulcer.
The following laboratory data were obtained: RBC 4.2 x 10*8/ul, WBC 5.0 x
10*8/ul, Hct 30%, Hgb 8.5 g/dl, serum iron 40 ug/dl, TIBC 460 ug/dl, serum ferritin
12 ng/ml. Examination of the bone marrow revealed the absence of iron stores.
This data is most consistent with which of the following conditions? a. iron
deficiency anemia
b. anemia of chronic disease
c. hemochromatosis
d. acute blood loss CORRECT ANSWER: a. iron deficiency anemia
A 32-year-old African-American traveling to Africa on business had been healthy
until
he began taking primaquine for prevention of malaria. He went to his physician
because
he felt faint and his urine was black. His CBC results are as follows: WBC 6.5 X
109/L
(6.5 X 103/^L); RBC 1.67 X 1012/L (1.67 x 1 O%L|_); hemoglobin level 50 g/L
(5.0
g/dL); hematocrit 0.15 L7L (15%); MCV 89.8 fL; MCHC 33.3 g/dL; platelet count
175
109/L (175,000/|jiL); reticulocyte25.0%. The defect in this disorder is caused
by an x
A. Amino acid substitution
B. Intrinsic red blood cell membrane defect
C. Enzyme deficiency in the hexose monophosphate shunt
D. Enzyme deficiency in the Embden-Meyerhof pathway CORRECT ANSWER: C.
Enzyme deficiency in the hexose monophosphate shunt
100% CORRECT ANSWERS
2026/2027
In the bone marrow, erythroid precursors are located:
A Surrounding macrophages in erythroid islands
B Adjacent to megakaryocytes along the adventitial cell lining
C Surrounding fat cells in apoptotic islands
D In the center of the hematopoietic cords CORRECT ANSWER: A Surrounding
macrophages in erythroid islands
Which of the following are characteristics of pluripotential hematopoietic stem
cells? I. Possess self-renewal ability II. Produces progenitor cells committed to a
particular cell lineage III. Morphologically unrecognizable IV. Expression of CD34
V. Expression of CD38
A. IandII
B. IandIV
C. I, II, III, and IV
D. I, II, III, IV, and V CORRECT ANSWER: D. I, II, III, IV, and V
Which of the following statements characterize erythropoietin (EPO) function? I.
Transforms the CFU-E into the earliest recognizable RBC precursor II. Increases
the rate of red blood cell production by the bone marrow III. Shortens the
maturation time of developing erythroid precursors IV. Decreases stimulation of
erythropoiesis when cellular hypoxia increases
A. I and II
B. I, II, and III
,C. II and III
D. I, II, III, and IV CORRECT ANSWER: B. I, II, and III
All of these are correct, except:
A. The kidneys recognize the tissue hypoxia through the peritubular cells of the
interstitium.
B. Tissue hypoxia is a prime stimulant for erythropoietin production.
C. Apoptosis is a physiologic process and its inhibition may also occur.
D. Erythropoietin acts mainly on pronormoblast. CORRECT ANSWER: D.
Erythropoietin acts mainly on pronormoblast.
Which of the following factors will result in an increase in oxygen delivery to the
tissues?
I. Increased blood pH II. High altitudes III. Increased hemoglobin binding of 2,3-
BPG
IV. Increased compensatory Hemoglobin F V. Increased carbon
dioxide
A. I, II, III, and IV
B. II and III
C. II, III, and V
D. I, II, III, and V CORRECT ANSWER: C. II, III,
and V
True for Sulfhemoglobinemia. Select all that apply. I. Reversible oxidation of
hemoglobin II. reported upon exposure to sulfur drugs e.g. sulfanilamide III.
Reported in patients with severe constipation in cases of severe bacteremia due
to Clostridium perfringens IV. Can be measured using Cyanmethemoglobin
method V. gives blood a mauve lavender discoloration
A. II and V
B. II and III
C. I, II, and III
D. II, III, and V CORRECT ANSWER: D. II, III,
and V
The EMP net gain of 2 ATP provides high energy phosphates to all of the
following
EXCEPT:
A. Maintenance of membrane
lipids
B. Power that cation pump needed for Na-K concentration pump and Ca
flux
, C. Preserve the shape and flexibility of the cellular
membrane
D. Gas exchange between the lungs and blood CORRECT ANSWER: D. Gas
exchange
between the lungs and
blood
What is the percent transferrin saturation for a patient with total serum iron of 63
mg/dL and TIBC of 420 mg/dL?
A. 0.15%
B. 1.2%
C. 12%
D. 15%
E. 80% CORRECT ANSWER: D. 15%
A 56-year-old man was admitted to the hospital for treatment of a bleeding ulcer.
The following laboratory data were obtained: RBC 4.2 x 10*8/ul, WBC 5.0 x
10*8/ul, Hct 30%, Hgb 8.5 g/dl, serum iron 40 ug/dl, TIBC 460 ug/dl, serum ferritin
12 ng/ml. Examination of the bone marrow revealed the absence of iron stores.
This data is most consistent with which of the following conditions? a. iron
deficiency anemia
b. anemia of chronic disease
c. hemochromatosis
d. acute blood loss CORRECT ANSWER: a. iron deficiency anemia
A 32-year-old African-American traveling to Africa on business had been healthy
until
he began taking primaquine for prevention of malaria. He went to his physician
because
he felt faint and his urine was black. His CBC results are as follows: WBC 6.5 X
109/L
(6.5 X 103/^L); RBC 1.67 X 1012/L (1.67 x 1 O%L|_); hemoglobin level 50 g/L
(5.0
g/dL); hematocrit 0.15 L7L (15%); MCV 89.8 fL; MCHC 33.3 g/dL; platelet count
175
109/L (175,000/|jiL); reticulocyte25.0%. The defect in this disorder is caused
by an x
A. Amino acid substitution
B. Intrinsic red blood cell membrane defect
C. Enzyme deficiency in the hexose monophosphate shunt
D. Enzyme deficiency in the Embden-Meyerhof pathway CORRECT ANSWER: C.
Enzyme deficiency in the hexose monophosphate shunt
