HESI A2 EXAM VERSION V1 A P 2026
STUDY GUIDE COMPREHENSIVE
QUESTIONS ANSWERS GRADED A+
◉ What is a tissue? Answer: A group of cells that act together to
perform a specific function.
◉ What are the fundamental tissues? Answer: Epithelial
Connective
Muscle
Nerve
(Elephants Can Make News)
◉ What is the function of epithelial cells? Answer: Cover, line, and
protect the body and the internal organs.
◉ What is the function of connective tissue? Answer: Framework of the
body. Provides support and structure to organs.
◉ What is neuroglia? Answer: The neurons and connective tissue cells
that compose nerve tissue.
◉ What ability does muscle tissue have? Answer: Ability to contract and
shorten.
,◉ What is muscle tissue classified as? Answer: Voluntary(skeletal
muscles) and involuntary(smooth & cardiac)
◉ What is meiosis? Answer: The cell division that takes place in the
gonads, i.e. the ovaries and testes.
◉ What two layers compose the skin? Answer: Epidermis and dermis.
◉ What is the epidermis? Answer: The outermost protective layer of
dead keratinized epithelial cells.
◉ What is the dermis? Answer: The underlying layer of connective
tissue with blood vessels, nerve endings, and the associated skin tissues.
◉ What are the layers of the epidermis? Answer: Corneum
Lucidum
Granulosum
Germivatum ( basale & spinosum)
Mnemonic: Candy Lions Growl Great.
◉ What does the protein pigment melanin protect against? Answer:
Radiation from the Sun
, ◉ What is the dermis composed of? Answer: Fibrous connective tissue
with nerve endings, blood vessels, sensory nerve endings, hair follicles,
and glands.
◉ What are the 2 types of sweat glands? Answer: ecrine & apocrine
◉ What do ecrine sweat glands produce? Answer: Sweat. Regulate body
temperature.
◉ What do apocrine sweat glands produce? Answer: Secretions contain
bits of cytoplasm from cells, attracting bacteria that produces body odor.
◉ What do sebaceous glands secrete? Answer: They secrete sebum
through the hair follicles, which lubricates the skin and prevents drying.
◉ What secretion produces oil? Answer: Holocrine secretion.
◉ What are sebaceous glands prone to during adolescence? Answer:
Becoming clogged and attracting bacteria.
◉ What protein composes the hair and skin? Answer: Keratin
◉ What makes the body's framework? Answer: Bone, cartilage,
ligaments & joints.