Describe red flags in a patient assessment that indicates a patient is
immunocompromised
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Medical history - Diseases that attack immune system (HIV), leukemia,
asplenia
Medications - Immunosuppressants, active chemotherapy, anti-rejection
meds
Special populations - Newborns (immature immune systems), Antivaxers
Briefly describe the patho of sepsis
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, Bacteria in the blood causes release of endotoxins (gram neg) and
exotoxins (gram pos) causing pro-inflammatory cytokines
Cytokines activate the complement and coagulation system, kinin system
and neutrophils, monocyte/macrophage activity, causing more cytokines
Causes endothelial cell dysfunction causing vasodilation and vascular
leaking
Define septic shock using clinical indicators
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Vasopressor requirement to maintain MAP >65mmHg
Serum lactate >2 despite adequate fluid management
State the results of endothelial cell dysfunction in sepsis
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Capillary leak and impaired vascular tone
Microvascular thrombosis
Cell adhesion
Tissue hypoxia
Apoptosis
Free radical damage
What are the symptoms of alcohol withdrawal
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immunocompromised
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Medical history - Diseases that attack immune system (HIV), leukemia,
asplenia
Medications - Immunosuppressants, active chemotherapy, anti-rejection
meds
Special populations - Newborns (immature immune systems), Antivaxers
Briefly describe the patho of sepsis
Give this one a try later!
, Bacteria in the blood causes release of endotoxins (gram neg) and
exotoxins (gram pos) causing pro-inflammatory cytokines
Cytokines activate the complement and coagulation system, kinin system
and neutrophils, monocyte/macrophage activity, causing more cytokines
Causes endothelial cell dysfunction causing vasodilation and vascular
leaking
Define septic shock using clinical indicators
Give this one a try later!
Vasopressor requirement to maintain MAP >65mmHg
Serum lactate >2 despite adequate fluid management
State the results of endothelial cell dysfunction in sepsis
Give this one a try later!
Capillary leak and impaired vascular tone
Microvascular thrombosis
Cell adhesion
Tissue hypoxia
Apoptosis
Free radical damage
What are the symptoms of alcohol withdrawal
Give this one a try later!
