NR 507 Final Exam Path Questions and Answers

NR 507 Final Exam Path Questions and Answers

1. Which of the following are considered the "first responders" of the innate
immune response?

A. Eosinophils

B. T-cells

C. IgM

D. Neutrophils: D. Neutrophils
2. Anaphylaxis is a hypersensitivity reaction.


A. type 1

B. type 2

C. type 3

D. type 4: A. Type 1
3. Type 2 (Cytotoxic) hypersensitivity reactions are mediated by:

A. IgE or IgG

B. IgA or IgE

C. IgG or IgM

D. IgM or IgA: C. IgG or IgM
4. Hives (urticaria) are an example of a:

A. Type 1 hypersensitivity reaction.

B. Type 2 hypersensitivity reaction.

C. Type 3 hypersensitivity reaction.

D. Type 4 hypersensitivity reaction.: A. Type 1 hypersensitivity reaction.



, NR 507 Final Exam Path Questions and Answers

5. Allergic contact dermatitis is an example of hypersen-
sitivity reaction.

A. Type 4

B. Type 1

C. Type 2

D. Type 3: A. Type 4
6. Type 1 Hypersensitivity reaction Mechanism:


A. Cytotoxic T cell-mediated

B. IgE action on mast cells

C. Tissue-specific destruction or impairment because of:
Antibody binding followed by lysis via complement
Antibody binding followed by macrophage phagocytosis
Antibody binding followed by neutrophil destruction
Antibody-dependent cell (NK)-mediated cytotoxicity, or
Antireceptor antibodies

D. Antigen-Antibody complex deposited in tissues: B. IgE action on mast cells
7. Type 2 Hypersensitivity reaction Mechanism:


A. Cytotoxic T cell-mediated

B. IgE action on mast cells

C. Tissue-specific destruction or impairment because of:
Antibody binding followed by lysis via complement
Antibody binding followed by macrophage phagocytosis
Antibody binding followed by neutrophil destruction
Antibody-dependent cell (NK)-mediated cytotoxicity, or
Antireceptor antibodies



, NR 507 Final Exam Path Questions and Answers

D. Antigen-Antibody complex deposited in tissues: C. Tissue-specific destruc-
tion or impairment because of:
Antibody binding followed by lysis via complement
Antibody binding followed by macrophage phagocytosis
Antibody binding followed by neutrophil destruction
Antibody-dependent cell (NK)-mediated cytotoxicity, or
Antireceptor antibodies
8. Type 3 Hypersensitivity reaction Mechanism:


A. Cytotoxic T cell-mediated

B. IgE action on mast cells

C. Tissue-specific destruction or impairment because of:
Antibody binding followed by lysis via complement
Antibody binding followed by macrophage phagocytosis
Antibody binding followed by neutrophil destruction
Antibody-dependent cell (NK)-mediated cytotoxicity, or
Antireceptor antibodies

D. Antigen-Antibody complex deposited in tissues: D. Antigen-Antibody com-
plex deposited in tissues
9. Type 4 Hypersensitivity reaction Mechanism:


A. Cytotoxic T cell-mediated

B. IgE action on mast cells

C. Tissue-specific destruction or impairment because of:
Antibody binding followed by lysis via complement
Antibody binding followed by macrophage phagocytosis
Antibody binding followed by neutrophil destruction
Antibody-dependent cell (NK)-mediated cytotoxicity, or
Antireceptor antibodies

D. Antigen-Antibody complex deposited in tissues: A. Cytotoxic T cell-mediated



, NR 507 Final Exam Path Questions and Answers

10. Type 4 Hypersensitivity reaction Example:

A. Contact dermatitis (e.g., poison ivy)

B. Hay fever

C. Raynaud's phenomenon

D. 1-ABO incompatibility
5-Graves' disease: A. Contact dermatitis (e.g., poison ivy)
11. Type 3 Hypersensitivity reaction Example:

A. Contact dermatitis (e.g., poison ivy)

B. Hay fever

C. Raynaud's phenomenon

D. 1-ABO incompatibility
5-Graves' disease: C. Raynaud's phenomenon
12. Type 2 Hypersensitivity reaction Example:

A. Contact dermatitis (e.g., poison ivy)

B. Hay fever

C. Raynaud's phenomenon

D. 1-ABO incompatibility
5-Graves' disease: D. 1-ABO incompatibility
5-Graves' disease
13. Type 1 Hypersensitivity reaction Example:

A. Contact dermatitis (e.g., poison ivy)

B. Hay fever

C. Raynaud's phenomenon