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Section 1: Cardiovascular Disorders (Questions 1-22)
Q1: A patient with heart failure reports a weight gain of 4 lbs over the past 3 days. What
is the nurse's priority action?
A. Assess the patient for other signs of fluid overload
B. Restrict the patient's fluid intake to 500 mL/day
C. Notify the health care provider immediately [CORRECT]
D. Document the weight and continue monitoring
Correct Answer: C
Rationale: A weight gain of greater than 2 to 3 lbs in 24 hours or more than 5 lbs in a
week is a critical indicator of fluid retention in heart failure and requires immediate
provider notification to adjust diuretic therapy. Options A, B, and D delay necessary
medical intervention; HESI prioritizes safety and acute changes requiring provider
orders.
Q2: The nurse is reviewing the echocardiogram results of a patient with heart failure.
The ejection fraction (EF) is noted to be 35%. How should the nurse classify this
patient's heart failure?
A. Heart failure with preserved ejection fraction (HFpEF)
B. Heart failure with mid-range ejection fraction (HFmrEF)
C. Heart failure with reduced ejection fraction (HFrEF) [CORRECT]
D. Right-sided heart failure
Correct Answer: C
Rationale: HFrEF (systolic heart failure) is defined by an ejection fraction of 40% or less
(often categorized as mild 36-40%, moderate 31-35%, severe ≤30%). An EF of 35%
falls into this category, guiding specific guideline-directed medical therapy (GDMT) such
as ARNIs, beta-blockers, and aldosterone antagonists.
Q3: A patient with HFrEF is prescribed sacubitril/valsartan (Entresto). What is the critical
nursing intervention regarding this medication?
A. Ensure a 36-hour washout period has passed since the last dose of an ACE inhibitor
[CORRECT]
B. Monitor the patient for hyperkalemia and angioedema, but no washout is needed
C. Administer the medication with food to prevent GI upset
D. Hold the medication if the patient's blood pressure is below 100/70 mmHg
Correct Answer: A
,Rationale: ACE inhibitors and ARNIs must not be used together due to the risk of
angioedema; a 36-hour washout period is required when switching from an ACE
inhibitor to sacubitril/valsartan. Option B is incorrect because the washout is mandatory.
Option C is incorrect because it can be taken with or without food. Option D is incorrect
because while BP is monitored, a specific hold parameter isn't the critical safety issue
compared to the ACEi interaction.
Q4: [EKG INTERPRETATION] The nurse reviews a 12-lead EKG and notes a regular
rhythm with absent P waves, a wide QRS complex greater than 0.12 seconds, and a
rate of 150 bpm. How should the nurse interpret this finding?
A. Atrial fibrillation
B. Supraventricular tachycardia (SVT)
C. Ventricular tachycardia (VT) [CORRECT]
D. Atrial flutter
Correct Answer: C
Rationale: Wide complex tachycardia (QRS > 0.12 sec) without P waves is
characteristic of ventricular tachycardia, a life-threatening dysrhythmia. Atrial fibrillation
has an irregularly irregular rhythm with narrow QRS (usually). SVT is typically narrow
complex. Atrial flutter has sawtooth P waves.
Q5: A patient with heart failure is prescribed furosemide (Lasix) 40 mg IV. Which
laboratory value should the nurse monitor closely due to this medication?
A. Sodium
B. Potassium [CORRECT]
C. Calcium
D. Magnesium
Correct Answer: B
Rationale: Loop diuretics like furosemide cause potassium wasting (hypokalemia),
which increases the risk of fatal dysrhythmias in heart failure patients who may also be
on digoxin. Close monitoring of potassium levels is a critical safety standard.
Q6: A patient with acute decompensated heart failure has severe dyspnea, orthopnea,
and crackles bilaterally. Their blood pressure is 90/60 mmHg. Which medication should
the nurse question if ordered?
A. Intravenous furosemide
B. Nitroglycerin IV [CORRECT]
C. Morphine sulfate
D. Supplemental oxygen
Correct Answer: B
Rationale: Nitroglycerin is a potent vasodilator used in pulmonary edema to reduce
preload, but it is contraindicated in hypotension (SBP < 90 mmHg) because it can cause
,severe, life-threatening hypotension. Furosemide and morphine may be used
cautiously, and oxygen is standard.
Q7: The nurse is educating a patient with chronic heart failure about sodium restriction.
Which statement by the patient indicates a need for further teaching?
A. "I will use fresh herbs and spices instead of salt when cooking."
B. "I will eat frozen dinners labeled 'low sodium' for convenience." [CORRECT]
C. "I will avoid canned soups and processed meats."
D. "I will read food labels to find foods with less than 600 mg of sodium per serving."
Correct Answer: B
Rationale: Many frozen or processed "low sodium" meals still contain high levels of
sodium that exceed the recommended restriction of <2000 mg/day for HF patients.
Relying on these without checking labels is a common pitfall. The other options
demonstrate correct dietary modifications for HF.
Q8: [MEDICATION CALCULATION] A patient with acute decompensated heart failure
and cardiogenic shock is prescribed dobutamine 2.5 mcg/kg/min. The patient weighs 70
kg. The pharmacy provides a premixed bag of 500 mg dobutamine in 250 mL D5W.
How many mL/hr should the nurse set the infusion pump to deliver the correct dose?
A. 5.25 mL/hr
B. 21 mL/hr [CORRECT]
C. 31.5 mL/hr
D. 42 mL/hr
Correct Answer: B
Rationale: Calculate the dose per minute: 2.5 mcg/kg/min × 70 kg = 175 mcg/min.
Calculate the dose per hour: 175 mcg/min × 60 min/hr = 10,500 mcg/hr (or 10.5 mg/hr).
Calculate the concentration: 500 mg / 250 mL = 2 mg/mL. Calculate the infusion rate:
10.5 mg/hr ÷ 2 mg/mL = 5.25 mL/hr... Wait. Let me recalculate. 10.5 mg/hr / 2 mg/mL =
5.25 mL/hr. My answer key says B is 21 mL/hr. Let me adjust the calculation in the
rationale to fit a correct HESI-style question. Let's change the dose to 10 mcg/kg/min.
10 mcg x 70 = 700 mcg/min. 700 x 60 = 42,000 mcg/hr = 42 mg/hr. 42 mg / 2 mg/mL =
21 mL/hr.
Q8: [MEDICATION CALCULATION] A patient with acute decompensated heart failure
and cardiogenic shock is prescribed dobutamine 10 mcg/kg/min. The patient weighs 70
kg. The pharmacy provides a premixed bag of 500 mg dobutamine in 250 mL D5W.
How many mL/hr should the nurse set the infusion pump to deliver the correct dose?
A. 5.25 mL/hr
B. 21 mL/hr [CORRECT]
C. 31.5 mL/hr
D. 42 mL/hr
, Correct Answer: B
Rationale: Calculate the dose per minute: 10 mcg/kg/min × 70 kg = 700 mcg/min.
Calculate the dose per hour: 700 mcg/min × 60 min/hr = 42,000 mcg/hr (or 42 mg/hr).
Calculate the concentration: 500 mg / 250 mL = 2 mg/mL. Calculate the infusion rate: 42
mg/hr ÷ 2 mg/mL = 21 mL/hr. HESI exams require precise multi-step dosage
calculations.
Q9: Which finding is a classic sign of right-sided heart failure?
A. Pulmonary crackles
B. Orthopnea
C. Jugular venous distension (JVD) [CORRECT]
D. Paroxysmal nocturnal dyspnea (PND)
Correct Answer: C
Rationale: Right-sided heart failure results in systemic venous congestion, leading to
jugular venous distension, hepatomegaly, and peripheral edema. Pulmonary crackles,
orthopnea, and PND are classic signs of left-sided heart failure due to pulmonary
congestion.
Q10: A patient with HFrEF asks the nurse why they must take a beta-blocker
(carvedilol) if it lowers their blood pressure and makes them feel tired. What is the
nurse's best response?
A. "Beta-blockers cure heart failure by strengthening the heart muscle."
B. "Although they lower blood pressure initially, they slow the heart rate and reduce the
workload on the heart, which prolongs life over time." [CORRECT]
C. "You can skip the beta-blocker on days you feel tired."
D. "Beta-blocks are only used to treat high blood pressure, not heart failure."
Correct Answer: B
Rationale: Beta-blockers are a cornerstone of GDMT for HFrEF because they
counteract sympathetic nervous system activation, slowing HR and reducing myocardial
oxygen demand, which improves survival. Patients must be educated that fatigue is a
common early side effect but the medication is vital for long-term outcomes.
Q11: [PRIORITIZATION] The nurse is caring for four patients with heart failure. Which
patient requires immediate intervention?
A. A patient who reports a new onset of a dry, non-productive cough
B. A patient whose daily weight is the same as yesterday
C. A patient who reports awakening gasping for breath during the night [CORRECT]
D. A patient who has 1+ pitting edema in bilateral ankles
Correct Answer: C
Rationale: Paroxysmal nocturnal dyspnea (PND) is a sign of acute pulmonary edema,
requiring immediate assessment and intervention (e.g., oxygen, diuretics, positioning).