HSPA) Exam Newest 2026-2027 Updated
100 Questions From Actual Exams
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Detailed Answers (Expert Verified Exam)
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1. Which of the following is the first step in the decontamination process?
A. Inspection
B. Sterilization
C. Cleaning
D. Packaging
C. Cleaning
explanation: Cleaning removes organic and inorganic material before
disinfection or sterilization.
2. A technician notices visible soil on an instrument after cleaning. What
should be done?
A. Send for sterilization
B. Wipe with alcohol
C. Reclean the instrument
D. Discard the instrument
C. Reclean the instrument
explanation: Instruments must be visibly clean before sterilization.
3. Which microorganism is the most resistant to sterilization?
A. Vegetative bacteria
B. Viruses
, C. Fungi
D. Bacterial spores
D. Bacterial spores
explanation: Spores are highly resistant and require proper sterilization
methods.
4. What is the purpose of enzymatic cleaners?
A. Kill bacteria
B. Break down organic material
C. Disinfect surfaces
D. Sterilize instruments
B. Break down organic material
explanation: Enzymes digest proteins, fats, and carbohydrates.
5. What temperature range is recommended for manual cleaning?
A. Cold water
B. Warm water
C. Hot water
D. Boiling water
B. Warm water
explanation: Warm water improves cleaning without coagulating proteins.
6. Which PPE is required in decontamination?
A. Gloves only
B. Mask only
C. Full PPE
D. None
C. Full PPE
explanation: Includes gloves, gown, mask, and eye protection.
7. What is the correct order of workflow in sterile processing?
A. Clean → Dirty → Sterile
B. Dirty → Clean → Sterile
C. Sterile → Clean → Dirty
D. Clean → Sterile → Dirty
, B. Dirty → Clean → Sterile
explanation: Prevents cross-contamination.
8. What does SPAULDING classification determine?
A. Cleaning methods
B. Packaging types
C. Level of disinfection/sterilization
D. Instrument lifespan
C. Level of disinfection/sterilization
explanation: Based on risk of infection.
9. Critical items must be:
A. Disinfected
B. Cleaned only
C. Sterilized
D. Washed
C. Sterilized
explanation: They enter sterile body areas.
10.Which sterilization method uses steam?
A. EO
B. Dry heat
C. Steam sterilization
D. Radiation
C. Steam sterilization
explanation: Uses moist heat under pressure.
11.What is the standard temperature for steam sterilization (gravity)?
A. 100°C
B. 121°C
C. 140°C
D. 160°C
B. 121°C
explanation: Standard gravity cycle temperature.