Pr of. Dr Shahina Y asm in
, Hypersensitivity
• When immune response results in exaggerated or
inappropriate reactions that are harmful to the host.
• First exposure to antigen leads to antibody formation
– sensitization.
• 2nd exposure to antigen leads to manifestation of
exaggerated response
• Four types of hypersensitivity
▫Type I Immediate (IgE mediated)
▫Type II Cytotoxic (IgG mediated)
▫Type III Immune complex (IgG mediated)
▫Type IV Delayed (Cell mediated)
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