NR 565 Advanced Pharmacology Final Exam 2026 |
Chamberlain Practice Test | Verified Questions &
Answers With Rationales (A+ Guide)
THIS EXAM INCLUDES:
• NR 565 Advanced Pharmacology Final Exam
• Chamberlain Practice Test
• Verified Questions & Answers
• Rationales included
• New 2026
,NR 565 Advanced Pharmacology Final Exam 2026
Question 1
In which patient population is Metformin contraindicated?
• A. Diabetics with HbA1c < 7.0%
• B. Patients older than 50
• C. Alcoholics
• D. Women suffering from infertility
Correct Answer: C. Alcoholics
Rationale: Metformin is contraindicated in chronic alcoholism due to increased
risk of lactic acidosis. Alcohol impairs hepatic gluconeogenesis and increases
lactate production.
Question 2
What lab value suggests metformin might be contraindicated?
• A. eGFR < 30
• B. Crea 0.8
• C. WBC 7.8
• D. Bun 17
Correct Answer: A. eGFR < 30
Rationale: Metformin is contraindicated when eGFR <30 due to accumulation and
lactic acidosis risk. At eGFR 30-45, dose reduction is recommended.
Question 3
What medication is contraindicated if a patient has a cardiac ejection fraction of
40%?
• A. Second Generation sulfonylureas
, • B. Thiazolidinediones
• C. Dopamine Agonist
• D. Glucosidase Inhibitor
Correct Answer: B. Thiazolidinediones
Rationale: TZDs (rosiglitazone, pioglitazone) cause fluid retention and can worsen
heart failure. Contraindicated in NYHA Class III/IV or reduced EF.
Question 4
First-line treatment for hyperthyroidism/Grave's disease?
• A. Methimazole
• B. Metoprolol
Correct Answer: A. Methimazole
Rationale: Methimazole is first-line antithyroid drug for Graves' disease (except
first trimester of pregnancy where PTU is preferred). Beta-blockers control
symptoms only.
Question 5
First-line treatment for newly diagnosed type 2 diabetes with adequate
renal/hepatic function?
• A. NovoLog Sliding Scale Insulin
• B. Liraglutide (Victoza)
• C. Oral Metformin
• D. Glipizide
Correct Answer: C. Oral Metformin
Rationale: Metformin is guideline-recommended first-line due to efficacy, safety,
low hypoglycemia risk, weight neutrality, and cardiovascular benefit.
, Question 6
Which medication is most likely to cause hypoglycemia?
• A. Metformin
• B. Insulin
• C. Incretin mimetics
• D. Thiazolidinediones
Correct Answer: B. Insulin
Rationale: Insulin has the highest hypoglycemia risk of all glucose-lowering
agents.
Question 7
Most expected symptoms of hypothyroidism?
• A. Shortness of breath, wheezing, fatigue
• B. Tachycardia, insomnia, weight loss, goiter
• C. Irritability, anxiety, dizziness, increased sweating
• D. Dry pale skin, brittle hair, fatigue, myxedema
Correct Answer: D. Dry pale skin, brittle hair, fatigue, myxedema
Rationale: Hypothyroidism slows metabolism → dry skin, hair changes, fatigue,
cold intolerance. Options B and C describe hyperthyroidism.
Question 8
Which drug class should be avoided in patients with active or high risk for
UTIs/genital infections?
• A. Thiazolidinediones
Chamberlain Practice Test | Verified Questions &
Answers With Rationales (A+ Guide)
THIS EXAM INCLUDES:
• NR 565 Advanced Pharmacology Final Exam
• Chamberlain Practice Test
• Verified Questions & Answers
• Rationales included
• New 2026
,NR 565 Advanced Pharmacology Final Exam 2026
Question 1
In which patient population is Metformin contraindicated?
• A. Diabetics with HbA1c < 7.0%
• B. Patients older than 50
• C. Alcoholics
• D. Women suffering from infertility
Correct Answer: C. Alcoholics
Rationale: Metformin is contraindicated in chronic alcoholism due to increased
risk of lactic acidosis. Alcohol impairs hepatic gluconeogenesis and increases
lactate production.
Question 2
What lab value suggests metformin might be contraindicated?
• A. eGFR < 30
• B. Crea 0.8
• C. WBC 7.8
• D. Bun 17
Correct Answer: A. eGFR < 30
Rationale: Metformin is contraindicated when eGFR <30 due to accumulation and
lactic acidosis risk. At eGFR 30-45, dose reduction is recommended.
Question 3
What medication is contraindicated if a patient has a cardiac ejection fraction of
40%?
• A. Second Generation sulfonylureas
, • B. Thiazolidinediones
• C. Dopamine Agonist
• D. Glucosidase Inhibitor
Correct Answer: B. Thiazolidinediones
Rationale: TZDs (rosiglitazone, pioglitazone) cause fluid retention and can worsen
heart failure. Contraindicated in NYHA Class III/IV or reduced EF.
Question 4
First-line treatment for hyperthyroidism/Grave's disease?
• A. Methimazole
• B. Metoprolol
Correct Answer: A. Methimazole
Rationale: Methimazole is first-line antithyroid drug for Graves' disease (except
first trimester of pregnancy where PTU is preferred). Beta-blockers control
symptoms only.
Question 5
First-line treatment for newly diagnosed type 2 diabetes with adequate
renal/hepatic function?
• A. NovoLog Sliding Scale Insulin
• B. Liraglutide (Victoza)
• C. Oral Metformin
• D. Glipizide
Correct Answer: C. Oral Metformin
Rationale: Metformin is guideline-recommended first-line due to efficacy, safety,
low hypoglycemia risk, weight neutrality, and cardiovascular benefit.
, Question 6
Which medication is most likely to cause hypoglycemia?
• A. Metformin
• B. Insulin
• C. Incretin mimetics
• D. Thiazolidinediones
Correct Answer: B. Insulin
Rationale: Insulin has the highest hypoglycemia risk of all glucose-lowering
agents.
Question 7
Most expected symptoms of hypothyroidism?
• A. Shortness of breath, wheezing, fatigue
• B. Tachycardia, insomnia, weight loss, goiter
• C. Irritability, anxiety, dizziness, increased sweating
• D. Dry pale skin, brittle hair, fatigue, myxedema
Correct Answer: D. Dry pale skin, brittle hair, fatigue, myxedema
Rationale: Hypothyroidism slows metabolism → dry skin, hair changes, fatigue,
cold intolerance. Options B and C describe hyperthyroidism.
Question 8
Which drug class should be avoided in patients with active or high risk for
UTIs/genital infections?
• A. Thiazolidinediones
