NSG 533 Advanced Pharmacology | Exam 1 |
Latest Guide Questions and Answers |
2026/2027 | Complete Solutions
‣ Antacid -✓✓Condition: GERD | Medication (Generic): Calcium carbonate |
Mechanism of Action: Neutralizes gastric acid | Indication / Use: Mild intermittent
GERD | Adult Dose: 500-1000 mg PRN | Duration: PRN | Key Adverse Effects:
Co
‣ Alginic acid -✓✓Condition: GERD | Medication (Generic): Alginic acid +
antacid | Mechanism of Action: Forms raft barrier | Indication / Use: Postprandial
reflux | Adult Dose: Per label | Duration: PRN | Key Adverse Effects: Bloating |
Contraind
‣ H2 receptor antagonist -✓✓Condition: GERD | Medication (Generic):
Famotidine | Mechanism of Action: Blocks H2 receptors | Indication / Use:
Mild/nocturnal GERD | Adult Dose: 20 mg BID | Duration: 4-8 wks | Key Adverse
Effects: Headache | Contrai
‣ Proton pump inhibitor -✓✓Condition: GERD | Medication (Generic):
Omeprazole | Mechanism of Action: Inhibits H+/K+ ATPase | Indication / Use:
First-line GERD | Adult Dose: 20-40 mg daily | Duration: 4-8 wks | Key Adverse
Effects: C. diff, fractures |
‣ Prokinetic -✓✓Condition: GERD | Medication (Generic): Metoclopramide |
Mechanism of Action: ↑ gastric emptying | Indication / Use: Refractory GERD |
Adult Dose: 5-10 mg QID | Duration: Short-term | Key Adverse Effects: EPS, TD |
Cont
‣ GABA-B agonist -✓✓Condition: GERD | Medication (Generic): Baclofen |
Mechanism of Action: ↓ LES relaxations | Indication / Use: Refractory GERD |
Adult Dose: 5-20 mg TID | Duration: Chronic | Key Adverse Effects: Sedation |
Contraindication
‣ Mucosal protectant -✓✓Condition: GERD | Medication (Generic): Sucralfate |
Mechanism of Action: Protective barrier | Indication / Use: Adjunct/alt GERD |
, Adult Dose: 1 g QID | Duration: 4-8 wks | Key Adverse Effects: Constipation |
Contraindication
‣ Triple therapy -✓✓Condition: H. pylori | Medication (Generic): Clarithromycin +
Amoxicillin + PPI | Mechanism of Action: Eradicates H. pylori | Indication / Use:
Clarithromycin triple | Adult Dose: Standard dosing | Duration: 14 days | Key
Adverse
‣ Quadruple therapy -✓✓Condition: H. pylori | Medication (Generic): Bismuth +
Metronidazole + Tetracycline + PPI | Mechanism of Action: Eradicates H. pylori |
Indication / Use: Bismuth quadruple | Adult Dose: Standard dosing | Duration: 10-
14 days
‣ Concomitant therapy -✓✓Condition: H. pylori | Medication (Generic):
Clarithromycin + Amoxicillin + Metronidazole + PPI | Mechanism of Action:
Eradicates H. pylori | Indication / Use: Concomitant | Adult Dose: Standard dosing
| Duration: 10-14 days
‣ Levofloxacin triple -✓✓Condition: H. pylori | Medication (Generic):
Levofloxacin + Amoxicillin + PPI | Mechanism of Action: Eradicates H. pylori |
Indication / Use: Salvage therapy | Adult Dose: Standard dosing | Duration: 10-14
days | Key Adverse E
‣ Rifabutin triple -✓✓Condition: H. pylori | Medication (Generic): Rifabutin +
Amoxicillin + PPI | Mechanism of Action: Eradicates resistant strains | Indication /
Use: Rescue therapy | Adult Dose: Standard dosing | Duration: 10 days | Key
Adverse E
‣ Prostaglandin analog -✓✓Condition: NSAID ulcer | Medication (Generic):
Misoprostol | Mechanism of Action: ↑ mucus & bicarb | Indication / Use: Ulcer
prevention | Adult Dose: 200 mcg QID | Duration: Chronic | Key Adverse Effects:
Diarrhea | Contrain
‣ COX-2 inhibitor -✓✓Condition: NSAID ulcer | Medication (Generic): Celecoxib
| Mechanism of Action: ↓ COX-1 injury | Indication / Use: Risk reduction | Adult
Dose: 200 mg daily | Duration: Chronic | Key Adverse Effects: CV risk |
Contraindication
Latest Guide Questions and Answers |
2026/2027 | Complete Solutions
‣ Antacid -✓✓Condition: GERD | Medication (Generic): Calcium carbonate |
Mechanism of Action: Neutralizes gastric acid | Indication / Use: Mild intermittent
GERD | Adult Dose: 500-1000 mg PRN | Duration: PRN | Key Adverse Effects:
Co
‣ Alginic acid -✓✓Condition: GERD | Medication (Generic): Alginic acid +
antacid | Mechanism of Action: Forms raft barrier | Indication / Use: Postprandial
reflux | Adult Dose: Per label | Duration: PRN | Key Adverse Effects: Bloating |
Contraind
‣ H2 receptor antagonist -✓✓Condition: GERD | Medication (Generic):
Famotidine | Mechanism of Action: Blocks H2 receptors | Indication / Use:
Mild/nocturnal GERD | Adult Dose: 20 mg BID | Duration: 4-8 wks | Key Adverse
Effects: Headache | Contrai
‣ Proton pump inhibitor -✓✓Condition: GERD | Medication (Generic):
Omeprazole | Mechanism of Action: Inhibits H+/K+ ATPase | Indication / Use:
First-line GERD | Adult Dose: 20-40 mg daily | Duration: 4-8 wks | Key Adverse
Effects: C. diff, fractures |
‣ Prokinetic -✓✓Condition: GERD | Medication (Generic): Metoclopramide |
Mechanism of Action: ↑ gastric emptying | Indication / Use: Refractory GERD |
Adult Dose: 5-10 mg QID | Duration: Short-term | Key Adverse Effects: EPS, TD |
Cont
‣ GABA-B agonist -✓✓Condition: GERD | Medication (Generic): Baclofen |
Mechanism of Action: ↓ LES relaxations | Indication / Use: Refractory GERD |
Adult Dose: 5-20 mg TID | Duration: Chronic | Key Adverse Effects: Sedation |
Contraindication
‣ Mucosal protectant -✓✓Condition: GERD | Medication (Generic): Sucralfate |
Mechanism of Action: Protective barrier | Indication / Use: Adjunct/alt GERD |
, Adult Dose: 1 g QID | Duration: 4-8 wks | Key Adverse Effects: Constipation |
Contraindication
‣ Triple therapy -✓✓Condition: H. pylori | Medication (Generic): Clarithromycin +
Amoxicillin + PPI | Mechanism of Action: Eradicates H. pylori | Indication / Use:
Clarithromycin triple | Adult Dose: Standard dosing | Duration: 14 days | Key
Adverse
‣ Quadruple therapy -✓✓Condition: H. pylori | Medication (Generic): Bismuth +
Metronidazole + Tetracycline + PPI | Mechanism of Action: Eradicates H. pylori |
Indication / Use: Bismuth quadruple | Adult Dose: Standard dosing | Duration: 10-
14 days
‣ Concomitant therapy -✓✓Condition: H. pylori | Medication (Generic):
Clarithromycin + Amoxicillin + Metronidazole + PPI | Mechanism of Action:
Eradicates H. pylori | Indication / Use: Concomitant | Adult Dose: Standard dosing
| Duration: 10-14 days
‣ Levofloxacin triple -✓✓Condition: H. pylori | Medication (Generic):
Levofloxacin + Amoxicillin + PPI | Mechanism of Action: Eradicates H. pylori |
Indication / Use: Salvage therapy | Adult Dose: Standard dosing | Duration: 10-14
days | Key Adverse E
‣ Rifabutin triple -✓✓Condition: H. pylori | Medication (Generic): Rifabutin +
Amoxicillin + PPI | Mechanism of Action: Eradicates resistant strains | Indication /
Use: Rescue therapy | Adult Dose: Standard dosing | Duration: 10 days | Key
Adverse E
‣ Prostaglandin analog -✓✓Condition: NSAID ulcer | Medication (Generic):
Misoprostol | Mechanism of Action: ↑ mucus & bicarb | Indication / Use: Ulcer
prevention | Adult Dose: 200 mcg QID | Duration: Chronic | Key Adverse Effects:
Diarrhea | Contrain
‣ COX-2 inhibitor -✓✓Condition: NSAID ulcer | Medication (Generic): Celecoxib
| Mechanism of Action: ↓ COX-1 injury | Indication / Use: Risk reduction | Adult
Dose: 200 mg daily | Duration: Chronic | Key Adverse Effects: CV risk |
Contraindication
