PATHOPHYSIOLOGY
EXAM 1
When does one get muscular dystrophy? - ANSWERS-it is inherited
What is muscular dystrophy? - ANSWERS-degeneration of skeletal
muscle. many forms. Abnormality based on the protein of dystrophin.
Causes muscle dysfunction, weakness, muscle loss and inflammation.
Fat and fibrous tissues replace the skeletal muscle fibers and weaken the
muscles.
What is the cause of fibromyalgia? - ANSWERS-unknown
What is fibromyalgia? - ANSWERS-Characterized by widespread pain
in all quadrants of the body. s/s: fatigue, insomnia, depression and
concentration problems.
What is myasthenia gravis? - ANSWERS-chronic autoimmune disease
that affects the neuromuscular function of voluntary muscles.
Explain how Myasthenia Gravis works. - ANSWERS-The acetylcholine
receptor antibodies destroy or block the acetylcholine receptors at the
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PATHOPHYSIOLOGY
EXAM 1
end of neurons. Manifestations include profound muscle weakness and
fatigue.
What is myasthenia graves crisis? - ANSWERS-When respiratory
distress occurs due to a weakened diaphragm muscle, leading to
hypoxemia and cardiac arrest
What is osteoarthritis? - ANSWERS-degenerative disorder associated
with aging and wear and tear from repetitive stress on the weight bearing
joints like the knees
How can osteoarthritis be characterized by? - ANSWERS-loss of
articular cartilage, calcification, wear of bone and bone spurs. Non
inflammatory, and the weight bearing joints are affected
Signs and symptoms that one might have osteoarthritis - ANSWERS-
localized joint pain and crepitus, bony enlargement, morning stiffness.
Heberden and bouchard nodes.
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PATHOPHYSIOLOGY
EXAM 1
What type of surgeries one might have that has osteoarthritis? -
ANSWERS-Total knee or hip surgeries
What type of disorder is rheumatoid arthritis? - ANSWERS-autoimmune
disorder
What is rheumatoid arthritis? - ANSWERS-systemic autoimmune
inflammatory condition. leads to accumulation of immune cells and
infiltration of synovial fluid. Results in bone erosion, cysts and fissures.
Signs and symptoms of rheumatoid arthritis - ANSWERS-bilateral
symmetric polyarthritis involving smaller joints, malaise, fatigue, and
diffuse musculoskeletal pain are common
What is psoriatic arthritis associated with? - ANSWERS-Psoriasis
What is psoriatic arthritis? - ANSWERS-Caused by genetics, t
lymphocytes and macrophages infiltrating skin and joints, producing
inflammatory cytokines.
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EXAM 1
Signs and symptoms of psoriatic arthritis - ANSWERS-oligoarthritis,
combined soft tissue and peripheral joint disease
What substance is affected with gout? - ANSWERS-high amounts of
uric acid
What is gout? - ANSWERS-disorder in which the disturbance of uric
acid metabolism leads to deposition of uric acid crystals in the joints.
risk increases with age. Characterized by hyperuricemia, and urate
crystal induced arthritis. Recurrent attacks of articular and periarticular
inflammation, renal and uric acid calculi.
What is Pathophysiology - ANSWERS-is the study of what happens
when the normal anatomy and physiology go wrong, causing disorder
and disease process of the human body.
What 4 things does pathophysiology include? - ANSWERS-Etiology,
Pathogenesis, Clinical Manifestations, and Treatment Implications
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