NR293 Pharmacology Week 4–7 Notes (PDF) | 2026 Chamberlain Pharm Review Guide

lOMoAR cPSD| 61371432




NR 293 – Pharmacology & Fundamentals Weeks 4-7
Review Notes | Actual verified Study | A+ Graded | 2026
Updates | 100% correct

WEEK 4


COAGULATION MODIFIERS
Anticoagulants & Antiplatelets




HEMOSTASIS REVIEW (YOU MUST KNOW THIS
FIRST)
Hemostasis = the body’s balance between:

1. Clot formation
2. Clot prevention
3. Clot breakdown

3 STAGES OF COAGULATION
Stage What Happens Why It Matters
Clot initiation Platelets form temporary plug Antiplatelets work here
Clot formation Fibrin strengthens clot Anticoagulants interfere
Fibrinolysis Clot dissolves Prevents emboli
🧠 Memory trick:
“Platelets PLUG → Fibrin FINISHES”




ANTICOAGULANTS vs ANTIPLATELETS (EXAM
FAVORITE)
Feature Anticoagulants Antiplatelets
Target Clotting factors Platelets
Primary use DVT, PE, AFib MI, stroke prevention

, lOMoAR cPSD| 61371432




Break clots? ❌ No ❌ No
Main risk Bleeding Bleeding
⚠️ NCLEX TRAP:
These drugs do NOT dissolve clots.




ANTICOAGULANTS

HEPARINS (Heparin, Enoxaparin)
MECHANISM OF ACTION
• Inactivates thrombin and Factor Xa
• Prevents clot formation  Prevents clot
extension



ADVERSE EFFECTS

Common Serious
Anemia Bleeding
Bruising HIT – Heparin-Induced Thrombocytopenia


NURSING IMPLICATIONS (TESTED HARD)
Action Why
Monitor aPTT (IV heparin) Therapeutic dosing
No routine labs for LMWH Predictable effect
Monitor platelets HIT risk
Avoid NSAIDs Bleeding risk
🧠 Memory trick:
“HEPARIN = HIT HAZARD”