,Table of Contents
MODULE 9 EXAM VERION 1.............................................. 2
MODULE 9 EXAM VERION 2............................................ 16
MODULE 9 EXAM STUDY GUIDE ....................................26
MODULE 9 EXAM VERION 1
1. Signs and symptoms of Addison's disease include each of the following
EXCEPT:
A. Hyperpigmentation
B. Hypotension
C. Weight loss
D. Hyperglycemia
Correct Answer: D. Hyperglycemia
Rationale:
Addison’s disease is a chronic adrenal insufficiency leading to decreased
cortisol and aldosterone, resulting in hypotension (from salt wasting), weight
loss, and hyperpigmentation (from elevated ACTH cross-reacting
,with melanocortin receptors). Hypoglycemia is common due to deficient
gluconeogenesis, not hyperglycemia.
---
2. Addison's disease is due to which of the following:
A. Thyroid dysfunction
B. Pituitary dysfunction
C. Adrenal gland dysfunction
D. Pancreatic dysfunction
Correct Answer: C. Adrenal gland dysfunction
Rationale:
Addison’s disease primarily arises from destruction or dysfunction of the
adrenal cortex, leading to glucocorticoid and mineralocorticoid deficiency. This
differentiates it from secondary adrenal insufficiency (pituitary) or disorders of
other endocrine glands.
---
3. T/F: An endocrine hormone is released into circulation to act on a target
organ.
Correct Answer: True
Rationale:
, By definition, endocrine hormones are secreted directly into the bloodstream
and exert their effects on distant target organs, distinguishing them from
paracrine (local) and autocrine (self-targeted) signaling.
4. What syndrome has an increased production of glucocorticoids?:
A. Addison’s
B. Cushing’s
C. Myxedema
D. Graves’
Correct Answer: B. Cushing’s
Rationale:
Cushing’s syndrome arises from chronic exposure to excessive glucocorticoids,
including increased endogenous production by the adrenal cortex or exogenous
administration. This contrasts with Addison’s disease, which involves adrenal
insufficiency leading to low glucocorticoid levels.
Myxedema and Graves’ disease pertain to thyroid pathologies, not
glucocorticoid disorders.
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5. The following are common signs and symptoms of Cushing
syndrome EXCEPT:
A. Central obesity
MODULE 9 EXAM VERION 1.............................................. 2
MODULE 9 EXAM VERION 2............................................ 16
MODULE 9 EXAM STUDY GUIDE ....................................26
MODULE 9 EXAM VERION 1
1. Signs and symptoms of Addison's disease include each of the following
EXCEPT:
A. Hyperpigmentation
B. Hypotension
C. Weight loss
D. Hyperglycemia
Correct Answer: D. Hyperglycemia
Rationale:
Addison’s disease is a chronic adrenal insufficiency leading to decreased
cortisol and aldosterone, resulting in hypotension (from salt wasting), weight
loss, and hyperpigmentation (from elevated ACTH cross-reacting
,with melanocortin receptors). Hypoglycemia is common due to deficient
gluconeogenesis, not hyperglycemia.
---
2. Addison's disease is due to which of the following:
A. Thyroid dysfunction
B. Pituitary dysfunction
C. Adrenal gland dysfunction
D. Pancreatic dysfunction
Correct Answer: C. Adrenal gland dysfunction
Rationale:
Addison’s disease primarily arises from destruction or dysfunction of the
adrenal cortex, leading to glucocorticoid and mineralocorticoid deficiency. This
differentiates it from secondary adrenal insufficiency (pituitary) or disorders of
other endocrine glands.
---
3. T/F: An endocrine hormone is released into circulation to act on a target
organ.
Correct Answer: True
Rationale:
, By definition, endocrine hormones are secreted directly into the bloodstream
and exert their effects on distant target organs, distinguishing them from
paracrine (local) and autocrine (self-targeted) signaling.
4. What syndrome has an increased production of glucocorticoids?:
A. Addison’s
B. Cushing’s
C. Myxedema
D. Graves’
Correct Answer: B. Cushing’s
Rationale:
Cushing’s syndrome arises from chronic exposure to excessive glucocorticoids,
including increased endogenous production by the adrenal cortex or exogenous
administration. This contrasts with Addison’s disease, which involves adrenal
insufficiency leading to low glucocorticoid levels.
Myxedema and Graves’ disease pertain to thyroid pathologies, not
glucocorticoid disorders.
---
5. The following are common signs and symptoms of Cushing
syndrome EXCEPT:
A. Central obesity
