NUR 210 Exam 1 PRiNciPlEs of PhaRmacology galEN collEgE
actUal Exam 2026/2027 – comPlEtE Exam-stylE QUEstioNs with
DEtailED RatioNalEs | Pass gUaRaNtEED – a+ gRaDED
1. A nurse is teaching a client about a newly prescribed medication. Which statement by the
client indicates a need for further teaching?
A. "I will take this medication exactly as prescribed."
B. "I can stop taking the medication when I feel better."
C. "I will tell my provider about any side effects I experience."
D. "I will keep a list of all my medications."
Answer: B
Rationale: Many medications must be taken for the full prescribed course, even if symptoms
improve. Stopping early can lead to treatment failure or drug resistance. Options A, C, and D are
correct statements.
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2. The nurse is administering a medication that has a high first-pass effect. Which route of
administration would avoid this effect?
A. Oral
B. Intravenous
C. Sublingual
D. Both B and C
Answer: D
, Rationale: The first-pass effect occurs when oral medications are metabolized by the liver before
reaching systemic circulation. Intravenous (B) and sublingual (C) routes bypass the liver,
avoiding first-pass metabolism.
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3. A drug has a half-life of 4 hours. How much of the drug will remain in the body after 12 hours?
A. 50%
B. 25%
C. 12.5%
D. 6.25%
Answer: C
Rationale: After 4 hours (1 half-life): 50% remains. After 8 hours (2 half-lives): 25% remains. After
12 hours (3 half-lives): 12.5% remains.
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4. A client is receiving a medication that binds to a receptor and produces a response. This drug
is known as an:
A. Agonist
B. Antagonist
C. Partial agonist
D. Competitive antagonist
Answer: A
Rationale: An agonist binds to a receptor and activates it, producing a response. An antagonist
(B) blocks the receptor and produces no response. A partial agonist (C) produces a weaker
response.
actUal Exam 2026/2027 – comPlEtE Exam-stylE QUEstioNs with
DEtailED RatioNalEs | Pass gUaRaNtEED – a+ gRaDED
1. A nurse is teaching a client about a newly prescribed medication. Which statement by the
client indicates a need for further teaching?
A. "I will take this medication exactly as prescribed."
B. "I can stop taking the medication when I feel better."
C. "I will tell my provider about any side effects I experience."
D. "I will keep a list of all my medications."
Answer: B
Rationale: Many medications must be taken for the full prescribed course, even if symptoms
improve. Stopping early can lead to treatment failure or drug resistance. Options A, C, and D are
correct statements.
---
2. The nurse is administering a medication that has a high first-pass effect. Which route of
administration would avoid this effect?
A. Oral
B. Intravenous
C. Sublingual
D. Both B and C
Answer: D
, Rationale: The first-pass effect occurs when oral medications are metabolized by the liver before
reaching systemic circulation. Intravenous (B) and sublingual (C) routes bypass the liver,
avoiding first-pass metabolism.
---
3. A drug has a half-life of 4 hours. How much of the drug will remain in the body after 12 hours?
A. 50%
B. 25%
C. 12.5%
D. 6.25%
Answer: C
Rationale: After 4 hours (1 half-life): 50% remains. After 8 hours (2 half-lives): 25% remains. After
12 hours (3 half-lives): 12.5% remains.
---
4. A client is receiving a medication that binds to a receptor and produces a response. This drug
is known as an:
A. Agonist
B. Antagonist
C. Partial agonist
D. Competitive antagonist
Answer: A
Rationale: An agonist binds to a receptor and activates it, producing a response. An antagonist
(B) blocks the receptor and produces no response. A partial agonist (C) produces a weaker
response.
